| La Casona Lake Jackson LLC | Accommodation and Food Services | $917,981 | $927,390 | 75 | $13.3M |  Research |
| Leo Martin Chevrolet, Inc. | Retail Trade | $788,000 | $796,096 | 61 | $15.4M | Research |
| Don Davis Dealerships, Inc. | Retail Trade | $778,014 | $783,503 | 60 | $15.1M | Research |
| Matula & Matula Construction, Inc. | Construction | $743,300 | $748,187 | 59 | $18.3M | Research |
| Matula & Matula Construction Inc. | Construction | $743,300 | $746,599 | 61 | $18.9M | Research |
| La Casona Lake Jackson LLC | Accommodation and Food Services | $657,300 | $664,804 | 88 | $15.6M | Research |
| Gulf Coast Garage Doors, LLC | Administrative and Support and Waste Management | $546,000 | $60,035 | 116 | $18.3M | Research |
| Audra Robinson | Accommodation and Food Services | $512,093 | $517,288 | 90 | $16.0M | Research |
| Gulf Coast Primary Home Care, Inc. | Health Care and Social Assistance | $505,600 | $508,548 | 125 | $21.4M | Research |
| Paytab Automotive Group, LLC | Retail Trade | $412,200 | $416,254 | 40 | $10.1M | Research |
| Lake Jackson Emergency Medical Services, Inc. | Transportation and Warehousing | $389,700 | $392,731 | 34 | N/A | Research |
| Km&l, LLC | Professional, Scientific, and Technical Services | $386,800 | $390,488 | 26 | $8.3M | Research |
| Killum Pest Control, Inc. | Administrative and Support and Waste Management | $352,400 | $354,389 | 34 | $7.4M | Research |
| Digestive & Liver Center, PA | Health Care and Social Assistance | $344,600 | $346,828 | 42 | $8.3M | Research |
| Hbt Baseball, LLC | Arts, Entertainment, and Recreation | $325,500 | $61,753 | 240 | $63.0M | Research |
| Wurst Haus German Deli | Accommodation and Food Services | $312,500 | $313,613 | 41 | $7.3M | Research |
| Digestive & Liver Center PA | Health Care and Social Assistance | $306,692 | $308,188 | 41 | $12.9M | Research |
| Bottenfield Pediatric Associates, Pllc. | Health Care and Social Assistance | $299,900 | $302,782 | 30 | $9.4M | Research |
| Iph Healthcare Services, Inc. | Health Care and Social Assistance | $288,100 | $289,979 | 23 | <$5M | Research |
| Brazosport Christian School | Educational Services | $271,900 | $273,427 | 42 | N/A | Research |
| Brazos Pointe Fellowship | Other Services (except Public Administration) | $268,300 | $270,549 | 65 | N/A | Research |
| Towworks, LLC | Transportation and Warehousing | $258,177 | $261,734 | 22 | <$5M | Research |
| Lake Jackson China Star LLC | Accommodation and Food Services | $244,489 | $246,505 | 26 | <$5M | Research |
| Platinum Sprinkler Company LLC | Unknown | $244,353 | $246,736 | 14 | N/A | Research |
| Brazosport Christian School | Educational Services | $233,800 | $235,088 | 37 | N/A | Research |