| Continental Dairy Facilities Southwest, LLC | Manufacturing | $1,461,825 | $1,480,369 | 118 | $41.6M | AI Deep Dive |
| Lamb County Hospital | Retail Trade | $999,700 | $1,006,356 | 105 | $16.4M | AI Deep Dive |
| Noltex Truss Littlefield, LP | Manufacturing | $284,267 | $286,455 | 49 | $48.6M | AI Deep Dive |
| Mp Southpark Pharmacy, LLC | Retail Trade | $232,500 | $234,335 | 43 | $7.5M | AI Deep Dive |
| John Roley Autocenter Ltd | Retail Trade | $221,500 | $223,339 | 20 | $5.0M | AI Deep Dive |
| Mp Southpark Pharmacy LLC | Retail Trade | $221,191 | $222,470 | 30 | $5.2M | AI Deep Dive |
| Littlefield Prescription Shop, LLC | Retail Trade | $198,100 | $199,544 | 25 | <$5M | AI Deep Dive |
| J&m Burns Transportation Inc. | Transportation and Warehousing | $191,775 | $193,567 | 13 | <$5M | AI Deep Dive |
| J&m Burns Transportation, Inc. | Transportation and Warehousing | $191,700 | $194,284 | 15 | <$5M | AI Deep Dive |
| Littlefield Prescription Shop LLC | Retail Trade | $188,017 | $189,140 | 21 | <$5M | AI Deep Dive |
| 2-W INC | Retail Trade | $122,500 | $123,503 | 13 | <$5M | AI Deep Dive |
| Wright Collision Center, Inc. | Other Services (except Public Administration) | $100,800 | $101,460 | 10 | <$5M | AI Deep Dive |
| Hooves N Horns INC | Finance and Insurance | $95,507 | $96,056 | 10 | $5.1M | AI Deep Dive |
| Fortenberry Roofing Co. | Construction | $90,500 | $91,415 | 7 | <$5M | AI Deep Dive |
| Cabinet and Doors by Cwd, LLC | Construction | $81,069 | $81,906 | 12 | <$5M | AI Deep Dive |
| Paint Nail Bar, LLC | Other Services (except Public Administration) | $63,900 | $64,566 | 14 | <$5M | AI Deep Dive |
| Perry Bussanmas | Agriculture, Forestry, Fishing and Hunting | $61,558 | $61,868 | 6 | <$5M | AI Deep Dive |
| Garyn Davis | Agriculture, Forestry, Fishing and Hunting | $60,298 | $60,504 | 5 | <$5M | AI Deep Dive |
| Nopalitos Restaurant LLC | Accommodation and Food Services | $59,182 | $59,512 | 3 | <$5M | AI Deep Dive |
| First Baptist Chruch | Other Services (except Public Administration) | $55,980 | $56,510 | 10 | N/A | AI Deep Dive |
| J W Haltom Dds, Inc. | Health Care and Social Assistance | $54,238 | $34,628 | 4 | <$5M | AI Deep Dive |
| Hrs Construction Limited Liability Corporation | Construction | $52,300 | $52,663 | 6 | $6.8M | AI Deep Dive |
| Ricky Yantis | Agriculture, Forestry, Fishing and Hunting | $48,700 | $49,003 | 3 | <$5M | AI Deep Dive |
| Enloe Electric Heating & Air Ltd. | Construction | $45,436 | $45,754 | 5 | <$5M | AI Deep Dive |
| Lamb County Veterinary Hospital, Ltd. | Professional, Scientific, and Technical Services | $44,030 | $44,472 | 7 | <$5M | AI Deep Dive |