| Health Care Unlimited, Inc. | Health Care and Social Assistance | $3,670,300 | $3,709,654 | 500 | $85.6M |  Research |
| Cornerstone Fitness Texas, LLC | Arts, Entertainment, and Recreation | $2,583,800 | $2,614,375 | 500 | $70.0M | Research |
| Hidalgo County Emergency Service Foundation | Health Care and Social Assistance | $2,559,600 | $0 | 250 | $57.9M | Research |
| Genco Energy Services, Inc. | Real Estate and Rental and Leasing | $2,503,000 | $2,535,985 | 149 | $67.3M | Research |
| Aim Media Texas Operating, LLC | Information | $2,137,500 | $2,162,081 | 295 | $49.5M | Research |
| Kenneth Fox Supply Company | Manufacturing | $2,114,000 | $2,138,210 | 276 | $97.4M | Research |
| Amtex General Contractors LLC | Construction | $2,047,102 | $2,074,074 | 260 | $88.6M | Research |
| Mansueto Ventures LLC | Information | $2,000,000 | $2,009,000 | 254 | $42.7M | Research |
| Castle Hospitality Ltd. | Accommodation and Food Services | $2,000,000 | $2,016,274 | 188 | $58.8M | Research |
| Med Care Emergency Medical Services | Health Care and Social Assistance | $1,953,700 | $1,977,687 | 253 | $58.6M | Research |
| Genco Energy Services, Inc. | Real Estate and Rental and Leasing | $1,855,000 | $1,875,735 | 53 | $23.9M | Research |
| Med Care Emergency Medical Services LLC | Health Care and Social Assistance | $1,802,700 | $1,828,639 | 287 | $46.5M | Research |
| Golden Aces INC | Accommodation and Food Services | $1,792,340 | $1,810,165 | 500 | $88.8M | Research |
| Rio Grande Valley Phc/ Cba, LLC | Health Care and Social Assistance | $1,691,800 | $1,707,966 | 500 | $85.6M | Research |
| Burns Motors Ltd | Retail Trade | $1,671,700 | $1,681,823 | 145 | $36.5M | Research |
| Burns Motors Ltd | Retail Trade | $1,671,700 | $1,681,080 | 138 | $34.8M | Research |
| Cs Auto, Ltd | Retail Trade | $1,538,400 | $1,547,883 | 141 | $35.5M | Research |
| Charles Clark Chevrolet Co. | Retail Trade | $1,532,700 | $1,542,442 | 130 | $32.8M | Research |
| Bert Ogden Mcallen Motors, Inc. | Retail Trade | $1,517,581 | $1,533,726 | 107 | $27.0M | Research |
| Castle Hospitality, Ltd. | Accommodation and Food Services | $1,510,600 | $1,521,857 | 236 | $73.8M | Research |
| Arepet Express LLC | Mining, Quarrying, and Oil and Gas Extraction | $1,360,000 | $706,332 | 111 | $6.7M | Research |
| Hjc Home Health Care Services, Inc. DBA Anthony's Home Healt | Health Care and Social Assistance | $1,359,177 | $1,391,774 | 500 | $85.6M | Research |
| D. Wilson Construction Company | Construction | $1,317,100 | $1,324,173 | 87 | $99.1M | Research |
| Palmer Steel Supplies, INC | Manufacturing | $1,237,495 | $1,244,208 | 131 | $32.0M | Research |
| Boggus Motors Sales II LLC | Retail Trade | $1,234,827 | $1,251,188 | 155 | $39.1M | Research |