| Muy Pizza Tejas, LLC | Accommodation and Food Services | $10,000,000 | $10,113,425 | 500 | $88.8M |  Research |
| Muy Hamburger Partners, LLC | Accommodation and Food Services | $10,000,000 | $10,361,644 | 250 | $44.4M | Research |
| Bill Miller Bar-B-Q Enterprises Ltd | Accommodation and Food Services | $10,000,000 | $10,115,342 | 500 | $88.8M | Research |
| Buffets LLC | Accommodation and Food Services | $10,000,000 | $10,113,973 | 500 | $88.8M | Research |
| Lewis Energy Group, LP | Mining, Quarrying, and Oil and Gas Extraction | $10,000,000 | $10,138,056 | 408 | $24.8M | Research |
| Muy Brands, LLC | Accommodation and Food Services | $8,655,100 | $8,968,818 | 31 | $5.5M | Research |
| Den Tex Central INC | Accommodation and Food Services | $8,051,780 | $8,145,754 | 500 | $88.8M | Research |
| Joeris General Contractors, Ltd. | Construction | $7,330,000 | $7,426,595 | 467 | $532.1M | Research |
| Our Lady of the Lake University of San Antonio | Educational Services | $6,604,600 | $6,694,679 | 455 | N/A | Research |
| United Core Management | Real Estate and Rental and Leasing | $6,504,987 | $857,181 | 500 | $72.5M | Research |
| Donald L Mooney Enterprises LLC | Administrative and Support and Waste Management | $5,920,900 | $1,951,901 | 500 | $78.7M | Research |
| Thomas J Henry Law Pllc | Professional, Scientific, and Technical Services | $5,756,900 | $5,822,986 | 487 | $118.3M | Research |
| Solutions Shared Services | Administrative and Support and Waste Management | $5,676,625 | $5,750,499 | 357 | $67.5M | Research |
| Mpower Holdings LLC | Health Care and Social Assistance | $5,624,287 | $5,690,841 | 426 | $133.7M | Research |
| Education Service Center Region 20 | Educational Services | $5,598,900 | $5,671,530 | 454 | N/A | Research |
| Mission Pharmacal Company | Manufacturing | $5,520,000 | $5,584,247 | 373 | $370.0M | Research |
| Urban Concrete Contractors Ltd | Construction | $5,464,000 | $5,529,264 | 207 | $47.9M | Research |
| United Biologics Holdings, LLC | Health Care and Social Assistance | $5,437,477 | $5,534,294 | 495 | $90.3M | Research |
| Surlean Meat Company | Manufacturing | $5,398,802 | $5,472,874 | 302 | $106.6M | Research |
| Renhill Staffing Services of Texas INC | Administrative and Support and Waste Management | $5,368,164 | $5,433,030 | 437 | $68.8M | Research |
| Frost & Sullivan | Professional, Scientific, and Technical Services | $5,185,100 | $5,244,338 | 251 | $52.2M | Research |
| South Texas Oncology & Hematology Pllc | Health Care and Social Assistance | $5,145,000 | $0 | 426 | $133.7M | Research |
| Stagg Restaurants, LLC | Accommodation and Food Services | $5,100,600 | $5,158,314 | 500 | $88.8M | Research |
| Southwestern Motor Transport, INC | Retail Trade | $5,067,985 | $5,127,956 | 386 | $97.3M | Research |
| Reynold Transportation, INC | Transportation and Warehousing | $5,004,600 | $5,073,293 | 452 | $91.1M | Research |