| Northeast Kingdom Human Services | Health Care and Social Assistance | $3,987,300 | $4,031,652 | 465 | N/A |  Research |
| Galvion Ballistics Ltd. | Manufacturing | $2,211,700 | $2,239,331 | 222 | $62.0M | Research |
| Poulin Grain, Inc. | Manufacturing | $1,400,000 | $1,412,351 | 125 | $44.1M | Research |
| Blissrite Pizza Company INC | Accommodation and Food Services | $674,200 | $678,873 | 117 | $20.8M | Research |
| Orleans Essex Visiting Nurse Association & Hospice, Inc. | Health Care and Social Assistance | $575,100 | $580,142 | 75 | N/A | Research |
| Built by Newport | Manufacturing | $505,356 | $508,181 | 60 | $15.7M | Research |
| Built by Newport Corporation | Manufacturing | $495,356 | $508,333 | 58 | $15.2M | Research |
| The Silver Corporation | Health Care and Social Assistance | $388,355 | $391,770 | 45 | $7.3M | Research |
| Metal Flex Welded Bellows INC | Other Services (except Public Administration) | $361,713 | $363,655 | 27 | $5.8M | Research |
| Metal Flex Welded Bellows INC | Other Services (except Public Administration) | $361,700 | $363,910 | 29 | $6.2M | Research |
| Newport Ambulance Service INC | Health Care and Social Assistance | $356,833 | $358,661 | 49 | $11.4M | Research |
| The Silver Corporation | Health Care and Social Assistance | $346,060 | $349,833 | 57 | $9.7M | Research |
| Hayes Ford INC | Retail Trade | $315,700 | $317,822 | 31 | $7.8M | Research |
| Eastside Restaurant Corp. | Accommodation and Food Services | $278,300 | $280,542 | 41 | $7.3M | Research |
| Track INC | Retail Trade | $215,700 | $218,306 | 19 | <$5M | Research |
| Northeast Pizza Enterprises Inc. | Accommodation and Food Services | $212,400 | $214,053 | 45 | $8.0M | Research |
| Francis L Pinard O. D. P.c | Health Care and Social Assistance | $203,500 | $205,005 | 19 | <$5M | Research |
| Francis L. Pinard O.d. PC | Health Care and Social Assistance | $203,500 | $205,713 | 19 | <$5M | Research |
| Northeast Kingdom Home Care, INC | Health Care and Social Assistance | $201,220 | $202,720 | 48 | $8.2M | Research |
| Northeast Kingdom Homecare Inc. | Health Care and Social Assistance | $199,777 | $201,726 | 38 | $6.5M | Research |
| Northeast Kingdom Learning Services, Inc. | Educational Services | $190,500 | $191,577 | 64 | $8.5M | Research |
| Kelley-View Farm, Inc. | Agriculture, Forestry, Fishing and Hunting | $182,517 | $184,687 | 17 | <$5M | Research |
| Kelley-View Farm Inc. | Agriculture, Forestry, Fishing and Hunting | $173,817 | $175,512 | 15 | <$5M | Research |
| Kingdom Construction, INC | Construction | $167,400 | $169,001 | 18 | $20.5M | Research |
| Kingdom Construction, INC | Construction | $167,400 | $169,358 | 19 | $21.6M | Research |