| Delta Response Team, LLC | Health Care and Social Assistance | $911,200 | $917,300 | 115 | $26.6M |  Research |
| Penelope INC | Retail Trade | $432,500 | $435,435 | 62 | $20.9M | Research |
| Penelope INC | Retail Trade | $426,556 | $428,973 | 62 | $20.9M | Research |
| Appomattox Glass & Storefront INC | Construction | $360,084 | $361,804 | 31 | $7.2M | Research |
| Appomattox Glass & Storefront, Inc. | Construction | $352,725 | $354,792 | 34 | $7.9M | Research |
| W. A. Stratton Construction Co. Inc. | Construction | $274,845 | $276,238 | 23 | $26.2M | Research |
| W.a. Stratton, Inc. | Construction | $266,600 | $269,105 | 18 | $20.5M | Research |
| Jamerson Building Supply, Inc. | Retail Trade | $214,700 | $216,076 | 27 | $5.6M | Research |
| Jv Ramsey Logging LLC | Agriculture, Forestry, Fishing and Hunting | $125,000 | $126,587 | 15 | <$5M | Research |
| W. D. Hackett Logging INC | Agriculture, Forestry, Fishing and Hunting | $120,900 | $121,652 | 10 | <$5M | Research |
| Campbell Lumber Company of Appomattox INC | Manufacturing | $117,200 | $118,222 | 15 | $14.9M | Research |
| Branch's Construction LLC | Wholesale Trade | $110,875 | $112,162 | 6 | <$5M | Research |
| Henderson Electrical Heating & Air LLC | Construction | $106,195 | $97,309 | 12 | <$5M | Research |
| Appomattox Auto Works, INC | Other Services (except Public Administration) | $105,700 | $106,256 | 10 | <$5M | Research |
| C.h. White Construction, Inc. | Construction | $104,000 | $104,575 | 10 | <$5M | Research |
| Hometown Pharmacy LLC | Retail Trade | $98,100 | $99,084 | 10 | <$5M | Research |
| Appomattox Drug Store, Inc. | Retail Trade | $97,000 | $97,757 | 11 | <$5M | Research |
| Estelle Robinson | Real Estate and Rental and Leasing | $87,500 | $88,217 | 10 | <$5M | Research |
| Appomattox Adult Healthcare Services, Incorporated | Health Care and Social Assistance | $85,362 | $86,026 | 24 | <$5M | Research |
| Missionary Food Bank | Health Care and Social Assistance | $84,000 | $84,602 | 11 | N/A | Research |
| Grace Hills Early Learning Center | Health Care and Social Assistance | $83,900 | $84,442 | 28 | N/A | Research |
| Ryan Atkins Masonry, LLC | Construction | $79,894 | $80,551 | 14 | <$5M | Research |
| Babcock Manor INC | Health Care and Social Assistance | $77,500 | $77,933 | 14 | <$5M | Research |
| Cornerstone Christian Academy of Appomattox | Educational Services | $73,000 | $73,354 | 14 | N/A | Research |
| Falling River Golf Tennis and Swimming Club INC | Arts, Entertainment, and Recreation | $72,432 | $73,325 | 39 | N/A | Research |