| Colonial Heights Operator | Health Care and Social Assistance | $1,750,000 | $1,604,791 | 212 | $36.1M |  Research |
| Fitt Scientific LLC | Professional, Scientific, and Technical Services | $1,500,000 | $1,520,384 | 102 | $14.3M | Research |
| Fitt Scientific LLC | Professional, Scientific, and Technical Services | $1,500,000 | $1,521,583 | 102 | $14.3M | Research |
| Rmm Enterprises INC | Construction | $553,300 | $555,836 | 42 | $47.9M | Research |
| James River Cardiology PC | Health Care and Social Assistance | $511,903 | $516,657 | 55 | $17.3M | Research |
| Colonial Plumbing & Heating Co. | Construction | $505,787 | $511,870 | 46 | $14.6M | Research |
| James River Cardiology, PC | Health Care and Social Assistance | $464,800 | $467,384 | 40 | $12.6M | Research |
| Colonial Heights Baptist Church | Other Services (except Public Administration) | $444,783 | $449,119 | 90 | N/A | Research |
| Ch Sedona Group LLC | Accommodation and Food Services | $374,256 | $377,906 | 78 | $13.8M | Research |
| Ariya Family Chiropractic Center PC | Health Care and Social Assistance | $333,172 | $334,514 | 25 | $5.9M | Research |
| Ch Sedona Group, LLC | Accommodation and Food Services | $321,400 | $323,247 | 43 | $7.6M | Research |
| Rent-E-Quip Inc. | Real Estate and Rental and Leasing | $305,543 | $307,792 | 24 | $10.8M | Research |
| Rent-E-Quip, Inc. | Real Estate and Rental and Leasing | $300,000 | $302,250 | 26 | $11.7M | Research |
| Colonial Wings LLC | Accommodation and Food Services | $298,291 | $300,277 | 63 | $11.2M | Research |
| Colonial Heights Collision Center INC | Other Services (except Public Administration) | $285,800 | $287,546 | 27 | $5.3M | Research |
| Ariya Family Chiropractic Center, PC | Health Care and Social Assistance | $274,430 | $275,975 | 25 | $5.9M | Research |
| Southeastern Engineering Sales, INC | Wholesale Trade | $256,600 | $258,247 | 12 | <$5M | Research |
| Drs. Gilbert and Farley, Od, PC | Health Care and Social Assistance | $242,157 | $228,113 | 13 | <$5M | Research |
| Drs Gilbert & Farley Od PC | Health Care and Social Assistance | $226,500 | $228,529 | 14 | <$5M | Research |
| Dsg, Inc. DBA Dance's Sporting Goods | Retail Trade | $224,200 | $164,623 | 38 | $8.9M | Research |
| Colonial Wings LLC | Accommodation and Food Services | $213,065 | $214,373 | 63 | $11.2M | Research |
| Roslyn Farm Corporation | Real Estate and Rental and Leasing | $205,000 | $232,405 | 15 | <$5M | Research |
| Colonial Heights Veterinary PC | Professional, Scientific, and Technical Services | $204,400 | $205,593 | 25 | <$5M | Research |
| The Appliance Place Inc. | Retail Trade | $197,800 | $200,531 | 22 | $6.7M | Research |
| E Alvin Small Funeral Home INC | Other Services (except Public Administration) | $197,696 | $201,780 | 22 | <$5M | Research |