| Jefferson Homebuilders Inc. | Manufacturing | $3,232,000 | $3,275,722 | 255 | $252.9M |  Research |
| Rappahannock Rapidan Community Services Board | Health Care and Social Assistance | $2,375,000 | $2,402,840 | 334 | N/A | Research |
| Mcclain & Co, Inc. | Real Estate and Rental and Leasing | $1,425,800 | $1,441,127 | 130 | $58.7M | Research |
| Merchants Grocery Company, Inc. | Wholesale Trade | $1,289,295 | $1,301,006 | 153 | $39.4M | Research |
| Culpeper Baptist Retiremnt Community, INC | Other Services (except Public Administration) | $1,262,554 | $1,275,636 | 206 | N/A | Research |
| Ridgeline Physician Services, LLC | Health Care and Social Assistance | $982,239 | $987,615 | 76 | $15.1M | Research |
| Culpeper Farmers Cooperative, INC | Retail Trade | $953,459 | $961,378 | 108 | $22.3M | Research |
| Neal Merchant Enterprises INC | Retail Trade | $909,900 | $918,923 | 80 | $20.2M | Research |
| Ridgeline Physician Services LLC | Health Care and Social Assistance | $878,990 | $884,459 | 85 | $26.7M | Research |
| Culpeper Imports LLC | Retail Trade | $701,112 | $707,760 | 50 | $12.6M | Research |
| Kent Excavating | Construction | $627,140 | $631,161 | 43 | $16.1M | Research |
| Chrysalis Counseling Centers, Inc. | Health Care and Social Assistance | $563,100 | $566,870 | 70 | $22.0M | Research |
| Chrysalis Counseling Centers Inc. | Health Care and Social Assistance | $531,639 | $538,565 | 68 | $21.3M | Research |
| Environmental Systems Service, Ltd | Professional, Scientific, and Technical Services | $508,022 | $512,755 | 50 | $10.1M | Research |
| Culpeper Motors LLC | Retail Trade | $461,000 | $465,648 | 38 | $9.6M | Research |
| Culpeper Wellness Foundation | Arts, Entertainment, and Recreation | $372,958 | $375,716 | 80 | N/A | Research |
| Culpeper Wellness Foundation | Arts, Entertainment, and Recreation | $372,900 | $375,604 | 98 | N/A | Research |
| Wls Motors, INC | Manufacturing | $357,808 | $360,988 | 24 | $6.3M | Research |
| Brenco Solutions LLC | Construction | $352,413 | $355,124 | 24 | $8.2M | Research |
| Moerings USA LLC | Retail Trade | $351,080 | $353,186 | 28 | $5.8M | Research |
| Walker Sand & Stone INC | Mining, Quarrying, and Oil and Gas Extraction | $347,757 | $351,370 | 38 | <$5M | Research |
| Culpeper Auto Parts, Inc. | Retail Trade | $345,300 | $349,329 | 49 | $13.2M | Research |
| Robert S Coleman Lumber Co INC | Manufacturing | $321,100 | $323,357 | 35 | $34.7M | Research |
| Maloney Insurance Agency Inc. | Finance and Insurance | $318,397 | $322,510 | 11 | $5.7M | Research |
| Culpeper Petroleum Cooperative Incorporated | Wholesale Trade | $317,355 | $321,516 | 37 | $9.5M | Research |