| Oran Safety Glass INC | Manufacturing | $1,251,000 | $1,259,549 | 145 | $143.8M | Research |
| Lifestar Ambulance Service INC | Health Care and Social Assistance | $795,495 | $804,356 | 84 | $19.5M | Research |
| Sadler Brothers Oil Company, Inc. | Wholesale Trade | $769,505 | $773,759 | 96 | $24.7M | Research |
| Greensville Manor, LLC | Health Care and Social Assistance | $615,938 | $622,907 | 56 | $9.5M | Research |
| Emporia Va Opco LLC | Health Care and Social Assistance | $483,125 | $489,044 | 53 | $9.0M | Research |
| Jakafi Behavioral Care Center | Health Care and Social Assistance | $481,000 | $485,997 | 73 | $11.8M | Research |
| Pw Foods LLC | Accommodation and Food Services | $471,200 | $476,390 | 104 | $18.5M | Research |
| Franklin Braid Manufacturing Co INC | Manufacturing | $434,945 | $439,345 | 80 | $28.2M | Research |
| Boyd Chevrolet-Buick-Gmc of Emporia Va., Inc. | Retail Trade | $367,102 | $370,916 | 40 | $10.1M | Research |
| Emporia Medical Associates, PC | Health Care and Social Assistance | $326,700 | $328,569 | 32 | $5.7M | Research |
| Emporia Medical Associates P. C. | Health Care and Social Assistance | $326,700 | $327,961 | 33 | $10.4M | Research |
| Real Tree Wood Corporation | Agriculture, Forestry, Fishing and Hunting | $304,260 | $305,919 | 27 | <$5M | Research |
| Hope First, LLC | Health Care and Social Assistance | $281,700 | $248,361 | 34 | $6.1M | Research |
| Redwine International, Inc. | Retail Trade | $273,152 | $275,148 | 23 | $6.2M | Research |
| Fosho Foods, LLC | Accommodation and Food Services | $251,000 | $252,889 | 71 | $12.6M | Research |
| Grizzard Home & Buildings LLC | Construction | $200,873 | $202,007 | 26 | $7.9M | Research |
| Slip-In Food Mart, Inc. | Retail Trade | $196,000 | $197,475 | 38 | $9.5M | Research |
| Southern Touch Health Care Services, Inc. | Health Care and Social Assistance | $190,300 | $191,447 | 46 | $7.9M | Research |
| Mid Atlantic Gin, LLC | Agriculture, Forestry, Fishing and Hunting | $185,000 | $186,223 | 15 | <$5M | Research |
| Moore Home Care Services, Inc. | Health Care and Social Assistance | $172,800 | $173,885 | 46 | $7.9M | Research |
| Fair Choice Home Health Care L.l.c | Health Care and Social Assistance | $168,600 | $169,487 | 42 | $7.2M | Research |
| B & M Truck Repair, LLC | Other Services (except Public Administration) | $163,700 | $165,219 | 15 | <$5M | Research |
| Jones Ltc Pharmacy INC | Retail Trade | $142,492 | $143,366 | 11 | <$5M | Research |
| Jones Ltc Pharmacy INC | Retail Trade | $142,492 | $143,257 | 11 | <$5M | Research |
| Family Ymca of Emporia-Greensville, Inc. | Arts, Entertainment, and Recreation | $141,400 | $143,073 | 51 | $7.1M | Research |