| Vaughan-Bassett Furniture Company Incorporated | Manufacturing | $3,624,482 | $3,660,528 | 432 | $113.1M | Research |
| Turman Hardwood Flooring, Inc. | Manufacturing | $1,233,000 | $1,246,242 | 175 | $173.6M | Research |
| Webb Furniture Enterprises LLC | Manufacturing | $846,481 | $851,282 | 111 | $29.1M | Research |
| Milo C. Cockerham, Inc. | Retail Trade | $831,432 | $839,007 | 151 | $50.5M | Research |
| Milo C Cockerham INC | Wholesale Trade | $831,432 | $835,543 | 145 | $37.3M | Research |
| Hills Trucking Company | Transportation and Warehousing | $623,400 | $627,417 | 57 | $13.0M | Research |
| Hills Trucking Company | Transportation and Warehousing | $614,303 | $618,245 | 57 | $11.5M | Research |
| Blue Ridge Home Health Care Services Inc. | Health Care and Social Assistance | $560,700 | $564,480 | 64 | $11.0M | Research |
| Gl Virginia Blue Ridge, LLC | Health Care and Social Assistance | $556,601 | $563,033 | 63 | $10.7M | Research |
| Gl Virginia Blue Ridge LLC | Health Care and Social Assistance | $556,601 | $561,039 | 33 | $5.6M | Research |
| Capriccio Elite LLC | Health Care and Social Assistance | $479,159 | $89,593 | 23 | <$5M | Research |
| Hansen Turbine Assemblies Corporation | Manufacturing | $450,000 | $423,386 | 42 | $10.3M | Research |
| Hansen Turbine Assemblies Corporation | Manufacturing | $418,717 | $423,994 | 42 | $11.0M | Research |
| Access Home Health Care and Rehabilitation LLC | Health Care and Social Assistance | $387,500 | $391,088 | 37 | $7.3M | Research |
| Access Home Health Care and Rehabilitation LLC | Health Care and Social Assistance | $349,999 | $353,643 | 47 | $8.1M | Research |
| Hills Fuel Trucking INC | Transportation and Warehousing | $327,300 | $329,391 | 32 | $6.4M | Research |
| Hills Fuel Trucking INC | Transportation and Warehousing | $327,003 | $329,219 | 24 | <$5M | Research |
| Southwest Virginia Home Health Care Inc. | Health Care and Social Assistance | $288,768 | $292,337 | 30 | $5.1M | Research |
| Lin-Mar Ltd. | Accommodation and Food Services | $254,600 | $256,344 | 66 | $11.7M | Research |
| E & L Diamond Electric Cooling & Heating Co Inc. | Construction | $237,800 | $240,686 | 29 | $9.2M | Research |
| E & L Diamond Electric Cooling and Heating Co. Inc. | Construction | $237,800 | $239,305 | 25 | $7.9M | Research |
| Blue Ridge Eye Care Associates, Pllc | Health Care and Social Assistance | $230,112 | $231,222 | 19 | <$5M | Research |
| Blue Ridge Eye Care Associates, Pllc | Health Care and Social Assistance | $230,100 | $231,600 | 24 | $5.6M | Research |
| Fielder Electric Motor Repair, Inc. | Wholesale Trade | $221,900 | $223,797 | 17 | $5.2M | Research |
| Grayson-Carroll-Wythe Mutual Insurance Company | Finance and Insurance | $195,100 | $196,201 | 14 | $7.2M | Research |