| Buchanan General Hospital INC | Health Care and Social Assistance | $1,942,304 | $1,960,540 | 208 | $41.3M |  Research |
| Buchanan General Hospital, INC | Health Care and Social Assistance | $1,689,953 | $1,708,918 | 231 | $45.8M | Research |
| Appalachian Regional Law School | Educational Services | $619,400 | $624,992 | 57 | N/A | Research |
| A, B & J Coal Company Inc. | Mining, Quarrying, and Oil and Gas Extraction | $532,800 | $537,267 | 49 | <$5M | Research |
| Paul's Fan Company | Manufacturing | $452,685 | $456,480 | 32 | $7.8M | Research |
| Appalachian Regional Law School | Educational Services | $444,000 | $447,860 | 49 | N/A | Research |
| Pauls Fan Company | Manufacturing | $422,400 | $425,478 | 41 | $10.7M | Research |
| Capital Coal Corporation | Mining, Quarrying, and Oil and Gas Extraction | $298,436 | $300,063 | 19 | <$5M | Research |
| Stiltner Mining, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $287,700 | $254,402 | 21 | <$5M | Research |
| Tri-State Clinic, Inc. | Health Care and Social Assistance | $258,984 | $261,106 | 17 | $5.3M | Research |
| Tri-State Clinic Inc. | Health Care and Social Assistance | $257,729 | $260,865 | 15 | <$5M | Research |
| K & R Contractors LLC | Construction | $200,236 | $202,661 | 17 | $5.2M | Research |
| Street Law Firm LLP | Professional, Scientific, and Technical Services | $191,185 | $193,787 | 16 | <$5M | Research |
| Terra Tech Engineering Services, P.c. | Professional, Scientific, and Technical Services | $188,900 | $190,962 | 9 | <$5M | Research |
| Street Law Firm LLP | Professional, Scientific, and Technical Services | $188,280 | $190,184 | 16 | <$5M | Research |
| K & R Contractors INC | Construction | $182,235 | $184,508 | 16 | $5.5M | Research |
| Buchanan Health Care LLC | Health Care and Social Assistance | $170,186 | $172,138 | 17 | <$5M | Research |
| J R S Enterprises Inc. | Transportation and Warehousing | $160,307 | $161,185 | 14 | <$5M | Research |
| Rife's T-V and Appliance Corporation | Retail Trade | $159,800 | $161,505 | 19 | <$5M | Research |
| Buchanan Health Care | Health Care and Social Assistance | $152,150 | $153,684 | 19 | $6.0M | Research |
| Mountain Therapy LLC | Health Care and Social Assistance | $149,700 | $150,873 | 12 | <$5M | Research |
| Terra Tech Engineering Services P.c. | Professional, Scientific, and Technical Services | $148,063 | $148,914 | 9 | <$5M | Research |
| Medical Park Pharmacy of Va, Inc. | Retail Trade | $133,200 | $134,328 | 31 | $5.4M | Research |
| B & M Construction INC | Construction | $124,820 | $126,356 | 16 | <$5M | Research |
| Rescue 33 Ambulance Service, Inc. | Health Care and Social Assistance | $117,855 | $84,053 | 12 | <$5M | Research |