| Marion Mold & Tool Inc. | Manufacturing | $711,860 | $717,048 | 44 | $10.8M |  Research |
| Marion Mold & Tool INC | Manufacturing | $711,800 | $715,973 | 44 | $10.8M | Research |
| Envision Eye Care | Health Care and Social Assistance | $554,992 | $561,545 | 61 | $14.3M | Research |
| Richardson Ambulance Service LLC | Health Care and Social Assistance | $552,900 | $558,520 | 83 | $19.2M | Research |
| Lane Engineering, Inc. | Professional, Scientific, and Technical Services | $494,000 | $496,815 | 34 | <$5M | Research |
| Envision Eye Care | Health Care and Social Assistance | $461,300 | $463,904 | 50 | $11.7M | Research |
| Southwest Virginia Legal Aid Society Inc. | Other Services (except Public Administration) | $419,000 | $421,319 | 29 | N/A | Research |
| Royal Oak Medical Associates, P.c. | Health Care and Social Assistance | $395,100 | $400,198 | 43 | $13.5M | Research |
| Med-Trip Express LLC | Transportation and Warehousing | $337,200 | $340,812 | 58 | $17.8M | Research |
| Teds, INC | Professional, Scientific, and Technical Services | $300,800 | $304,467 | 21 | <$5M | Research |
| Marion Chevrolet Buick Gmc, Inc. | Retail Trade | $286,900 | $289,549 | 24 | $6.0M | Research |
| Appalachian Oral Maxillofacial Surgery Ltd | Health Care and Social Assistance | $283,200 | $286,311 | 11 | <$5M | Research |
| Med-Trip Express, LLC | Transportation and Warehousing | $271,700 | $275,072 | 45 | $13.8M | Research |
| H.s. Williams Company, Inc. | Construction | $256,800 | $258,355 | 21 | $23.9M | Research |
| Rock Bottom Express, LLC | Transportation and Warehousing | $222,930 | $224,326 | 25 | $9.7M | Research |
| Mountain View Pediatrics, P.c. | Health Care and Social Assistance | $206,800 | $208,811 | 19 | $6.0M | Research |
| Mountain View Pediatrics PC | Health Care and Social Assistance | $206,800 | $209,055 | 19 | $6.0M | Research |
| H.s. Williams Company Inc. | Construction | $196,300 | $197,209 | 21 | $23.9M | Research |
| Fox Valley, LLC | Transportation and Warehousing | $191,800 | $193,418 | 35 | <$5M | Research |
| Fox Valley LLC | Transportation and Warehousing | $191,800 | $192,767 | 18 | <$5M | Research |
| General Francis Marion Hotel LLC | Accommodation and Food Services | $186,300 | $183,277 | 25 | $7.8M | Research |
| Summit Beverage Group LLC | Manufacturing | $178,870 | $180,600 | 32 | $11.3M | Research |
| Summit Beverage Group, LLC | Manufacturing | $156,800 | $158,119 | 26 | $9.2M | Research |
| James L. Gates Dds, P.c. | Health Care and Social Assistance | $149,300 | $150,246 | 16 | <$5M | Research |
| James L. Gates DDS PC | Health Care and Social Assistance | $149,300 | $150,147 | 16 | <$5M | Research |