| Elk Knob INC | Construction | $340,900 | $343,926 | 33 | $10.2M |  Research |
| Cornerstone Therapy Services Inc. | Health Care and Social Assistance | $235,800 | $236,995 | 18 | <$5M | Research |
| Cornerstone Therapy Services, Inc. | Health Care and Social Assistance | $209,800 | $211,915 | 18 | <$5M | Research |
| Jessee Stone Company | Mining, Quarrying, and Oil and Gas Extraction | $204,200 | $205,754 | 18 | <$5M | Research |
| Shawn & Corey Transport INC | Transportation and Warehousing | $124,700 | $126,190 | 10 | <$5M | Research |
| Shawn & Corey Transport | Transportation and Warehousing | $124,700 | $125,493 | 8 | <$5M | Research |
| Old Virginia Hand Hewn Log Homes INC | Manufacturing | $122,500 | $123,383 | 25 | $24.8M | Research |
| Timberland Resources LLC | Agriculture, Forestry, Fishing and Hunting | $93,400 | $94,019 | 11 | <$5M | Research |
| Old Virginia Hand Hewn Log Homes INC | Construction | $86,300 | $86,822 | 14 | <$5M | Research |
| Pennington Drug Center INC | Retail Trade | $84,400 | $84,839 | 12 | <$5M | Research |
| Mclin INC | Accommodation and Food Services | $81,400 | $81,786 | 16 | <$5M | Research |
| Lee Family Dental Plc | Health Care and Social Assistance | $80,400 | $80,777 | 8 | <$5M | Research |
| Moving Forward Physical Therapy, Inc. | Health Care and Social Assistance | $79,600 | $80,174 | 9 | <$5M | Research |
| Fannon Brothers Tire, Inc. | Retail Trade | $73,000 | $78,297 | 11 | <$5M | Research |
| Moving Forward Physical Therapy, Inc. | Health Care and Social Assistance | $68,000 | $68,425 | 9 | <$5M | Research |
| Corey Ely Logging LLC | Agriculture, Forestry, Fishing and Hunting | $66,800 | $67,598 | 6 | <$5M | Research |
| Corey Ely Logging LLC | Agriculture, Forestry, Fishing and Hunting | $66,800 | $28,882 | 3 | <$5M | Research |
| Timberland Resources | Agriculture, Forestry, Fishing and Hunting | $65,900 | $66,490 | 13 | <$5M | Research |
| Southwest Heating and Air Conditioning | Construction | $64,400 | $64,896 | 11 | <$5M | Research |
| Rooster's Pub Inc. | Accommodation and Food Services | $63,393 | $64,018 | 16 | <$5M | Research |
| Synergy Biofuels LLC | Manufacturing | $61,873 | $62,963 | 13 | $12.9M | Research |
| Lee Propane of Pennington Gap INC | Retail Trade | $61,100 | $61,570 | 8 | <$5M | Research |
| Lee Family Dental Plc | Health Care and Social Assistance | $59,500 | $59,948 | 7 | <$5M | Research |
| Mclin INC | Accommodation and Food Services | $56,900 | $57,365 | 12 | <$5M | Research |
| Synergy Biofuels LLC | Manufacturing | $55,950 | $0 | 5 | <$5M | Research |