| Harvey Chevrolet Corp | Retail Trade | $754,400 | $764,135 | 66 | $16.6M | AI Deep Dive |
| Child Adolescent Health Associates of the New River Valley, | Health Care and Social Assistance | $669,545 | $598,856 | 58 | $18.2M | AI Deep Dive |
| Child Adolescent Health Associates of the New River Valley P | Health Care and Social Assistance | $573,895 | $578,247 | 49 | $15.4M | AI Deep Dive |
| Motion Control Systems | Manufacturing | $499,883 | $503,132 | 50 | $13.1M | AI Deep Dive |
| Motion Control Systems | Manufacturing | $499,883 | $504,576 | 49 | $12.8M | AI Deep Dive |
| Thompson Tire Co Inc. | Retail Trade | $424,800 | $417,365 | 48 | $13.0M | AI Deep Dive |
| New River Heating and Air Conditioning, INC | Construction | $416,600 | $420,477 | 39 | $12.3M | AI Deep Dive |
| Thompsontire Co INC | Other Services (except Public Administration) | $415,000 | $417,558 | 48 | $9.4M | AI Deep Dive |
| Thompson Services INC | Administrative and Support and Waste Management | $329,100 | $332,409 | 152 | $32.9M | AI Deep Dive |
| Mc3 Solutions, LLC | Construction | $262,585 | $263,854 | 18 | $20.5M | AI Deep Dive |
| Twisted Sisters Pizza INC | Accommodation and Food Services | $246,627 | $249,168 | 34 | $6.0M | AI Deep Dive |
| Mvf Raj Corporation | Accommodation and Food Services | $230,200 | $231,581 | 25 | $7.8M | AI Deep Dive |
| Price-Williams Realty, Inc. | Real Estate and Rental and Leasing | $224,300 | $226,537 | 27 | <$5M | AI Deep Dive |
| H.t. Bowling Inc. | Construction | $216,300 | $218,577 | 27 | $10.1M | AI Deep Dive |
| Radford Family Dental, Inc. | Health Care and Social Assistance | $211,500 | $213,574 | 29 | $6.7M | AI Deep Dive |
| Aim Concrete Foundations INC | Construction | $196,700 | $198,581 | 19 | <$5M | AI Deep Dive |
| Taylor Hollow Construction LLC | Construction | $192,400 | $194,841 | 20 | $6.1M | AI Deep Dive |
| Twisted Sisters Pizza, Inc. | Accommodation and Food Services | $176,000 | $177,524 | 47 | $8.3M | AI Deep Dive |
| Bondurant Realty Corporation | Real Estate and Rental and Leasing | $175,500 | $176,625 | 17 | <$5M | AI Deep Dive |
| Mvf Raj Corporation | Accommodation and Food Services | $172,500 | $174,757 | 23 | $7.2M | AI Deep Dive |
| Metal Processing Inc. | Manufacturing | $162,200 | $163,262 | 14 | <$5M | AI Deep Dive |
| Thermasteel Incorporated | Manufacturing | $151,431 | $0 | 19 | <$5M | AI Deep Dive |
| Alexander Industries, Inc. | Manufacturing | $146,450 | $147,805 | 15 | <$5M | AI Deep Dive |
| Professional Rehab Associates | Health Care and Social Assistance | $136,660 | $138,194 | 10 | <$5M | AI Deep Dive |
| Four Sisters, INC | Accommodation and Food Services | $135,900 | $136,753 | 45 | $8.0M | AI Deep Dive |