| The Medical Team, Inc. | Health Care and Social Assistance | $10,000,000 | $10,110,959 | 500 | $85.6M | Research |
| Architecture INC | Professional, Scientific, and Technical Services | $10,000,000 | $1,252,839 | 63 | $19.5M | Research |
| Maryland and Virginia Milk Producers Cooperative Association | Manufacturing | $8,392,279 | $8,496,017 | 500 | $176.5M | Research |
| Applied Information Sciences, Inc. | Professional, Scientific, and Technical Services | $7,675,887 | $7,228,966 | 321 | $66.4M | Research |
| Ats Esop Holdings Inc. | Professional, Scientific, and Technical Services | $7,463,000 | $421,206 | 291 | $40.7M | Research |
| National Wildlife Federation | Other Services (except Public Administration) | $6,029,807 | $6,072,444 | 334 | N/A | Research |
| Adams Communication & Engineering Technology, Inc. | Professional, Scientific, and Technical Services | $6,026,777 | $6,095,301 | 278 | $57.5M | Research |
| Thompson Hospitality Services LLC | Accommodation and Food Services | $5,868,551 | $5,963,091 | 500 | $93.3M | Research |
| Matchbox Management, LLC | Accommodation and Food Services | $5,566,272 | $5,642,654 | 500 | $88.8M | Research |
| Pragmatics, Inc. | Public Administration | $5,548,037 | $5,621,453 | 195 | N/A | Research |
| Hydrogeologic INC | Administrative and Support and Waste Management | $5,367,700 | $0 | 272 | $51.5M | Research |
| Metrostar Systems, Inc. | Professional, Scientific, and Technical Services | $5,084,100 | $4,421,746 | 250 | $51.7M | Research |
| Converged Security Solutions, LLC | Professional, Scientific, and Technical Services | $5,017,200 | $5,091,290 | 296 | $30.6M | Research |
| Intelligent Waves, LLC | Wholesale Trade | $4,793,900 | $4,848,897 | 212 | $64.9M | Research |
| Clarabridge INC | Information | $4,790,185 | $4,846,070 | 256 | $43.0M | Research |
| Ventera Corporation | Professional, Scientific, and Technical Services | $4,303,653 | $4,353,881 | 221 | $30.9M | Research |
| Iba Proton Therapy INC | Professional, Scientific, and Technical Services | $4,121,061 | $4,177,175 | 252 | $52.1M | Research |
| Golden Key Group, LLC | Professional, Scientific, and Technical Services | $4,000,000 | $4,045,222 | 325 | $33.6M | Research |
| American Society of Civil Engineers | Information | $3,904,700 | $4,768,767 | 250 | N/A | Research |
| Goal Group, INC | Professional, Scientific, and Technical Services | $3,834,000 | $3,878,462 | 188 | $38.9M | Research |
| Cybermedia Technologies, Inc. | Professional, Scientific, and Technical Services | $3,515,100 | $3,557,476 | 333 | $34.5M | Research |
| Perfect Sense, Inc. | Information | $3,405,800 | $3,445,818 | 160 | $26.9M | Research |
| Echo 360 INC | Professional, Scientific, and Technical Services | $3,298,100 | $3,335,753 | 115 | $23.8M | Research |
| Administrative Control Services, Inc. | Administrative and Support and Waste Management | $3,288,700 | $3,326,520 | 153 | $28.9M | Research |
| Seneca Resources, LLC | Professional, Scientific, and Technical Services | $3,271,600 | $3,309,769 | 277 | $38.8M | Research |