| The Roanoker Restaurant, Inc. | Accommodation and Food Services | $192,500 | $193,808 | 19 | <$5M | AI Deep Dive |
| Generation Solutions Personal Care of Roanoke LLC | Health Care and Social Assistance | $192,300 | $193,587 | 71 | $12.2M | AI Deep Dive |
| Fah LLC | Accommodation and Food Services | $192,108 | $193,860 | 46 | $8.2M | AI Deep Dive |
| Rrrr LLC | Accommodation and Food Services | $192,013 | $193,475 | 20 | <$5M | AI Deep Dive |
| Ez Rampz, Inc. | Manufacturing | $191,900 | $193,041 | 22 | $5.8M | AI Deep Dive |
| Famous Anthony's 460 East Inc. | Accommodation and Food Services | $191,782 | $193,162 | 26 | <$5M | AI Deep Dive |
| Harvest Roanoke LLC | Accommodation and Food Services | $191,348 | $193,560 | 38 | $6.7M | AI Deep Dive |
| Lee Kesler Construction, Inc. | Construction | $191,000 | $193,037 | 15 | $17.1M | AI Deep Dive |
| Comer Enterprises INC | Construction | $191,000 | $192,056 | 31 | $10.2M | AI Deep Dive |
| Comer Enterprises INC | Construction | $190,900 | $191,971 | 31 | $10.2M | AI Deep Dive |
| Corned Beef & Company | Accommodation and Food Services | $190,741 | $192,522 | 26 | <$5M | AI Deep Dive |
| Tanglewood Hospitality Inc. | Accommodation and Food Services | $189,960 | $191,922 | 49 | $15.3M | AI Deep Dive |
| Orchard Hills Church | Other Services (except Public Administration) | $189,760 | $190,899 | 30 | N/A | AI Deep Dive |
| Kabuki Corporation | Accommodation and Food Services | $189,739 | $191,381 | 38 | $6.7M | AI Deep Dive |
| Anderson & Reed LLP | Professional, Scientific, and Technical Services | $188,100 | $189,260 | 20 | $6.4M | AI Deep Dive |
| First Choice Title Services, LLC | Professional, Scientific, and Technical Services | $187,510 | $189,241 | 15 | <$5M | AI Deep Dive |
| Greystar Construction Group LLC | Construction | $186,772 | $208,787 | 20 | <$5M | AI Deep Dive |
| Psychological Health Roanoke, PC | Health Care and Social Assistance | $186,709 | $189,141 | 22 | $5.2M | AI Deep Dive |
| St. John's Episcopal Church | Other Services (except Public Administration) | $186,600 | $188,347 | 32 | N/A | AI Deep Dive |
| Roanoke Stamp & Seal Co. | Manufacturing | $186,200 | $187,560 | 18 | $17.9M | AI Deep Dive |
| Cave Spring Veterinary Clinic Inc. | Professional, Scientific, and Technical Services | $185,800 | $187,093 | 30 | <$5M | AI Deep Dive |
| Johnson Orthodontics, Ltd | Health Care and Social Assistance | $185,535 | $187,894 | 14 | <$5M | AI Deep Dive |
| Roanoke Airport Transportation Service, Inc. | Transportation and Warehousing | $185,100 | $97,630 | 45 | $43.6M | AI Deep Dive |
| Mark R. Finkler, D.v.m., P.c. | Professional, Scientific, and Technical Services | $184,105 | $185,089 | 23 | <$5M | AI Deep Dive |
| Lcm Corporation | Administrative and Support and Waste Management | $184,057 | $186,843 | 14 | <$5M | AI Deep Dive |