| Follansbee Pharmacy INC | Retail Trade | $566,300 | $571,746 | 56 | $9.8M |  Research |
| Murphy Consolidated Industries, Inc. | Real Estate and Rental and Leasing | $526,767 | $530,620 | 28 | $12.7M | Research |
| Murphy Consolidated Industries Inc. | Management of Companies and Enterprises | $484,358 | $486,998 | 17 | <$5M | Research |
| Lombardi Development Company Inc. | Construction | $326,406 | $328,767 | 30 | $34.2M | Research |
| Lombardi Development Company, Inc. | Construction | $297,897 | $300,011 | 27 | $30.8M | Research |
| Lyle's Auto LLC | Retail Trade | $212,700 | $214,461 | 20 | $5.0M | Research |
| Brooke County Committee On Aging INC | Other Services (except Public Administration) | $105,000 | $106,303 | 35 | $6.7M | Research |
| Oasis Transport, LLC | Transportation and Warehousing | $97,865 | $98,680 | 8 | <$5M | Research |
| Golden Oaks Residential Board and Care INC | Health Care and Social Assistance | $94,617 | $95,022 | 20 | <$5M | Research |
| Golden Oaks Residential Board and Care INC | Health Care and Social Assistance | $89,402 | $90,028 | 21 | <$5M | Research |
| Hood's Pharmacy, Inc. | Retail Trade | $74,918 | $75,531 | 12 | <$5M | Research |
| Michael Pipo | Health Care and Social Assistance | $55,987 | $56,386 | 6 | <$5M | Research |
| Sandhill Crane Partners, LLC | Health Care and Social Assistance | $53,525 | $53,913 | 21 | <$5M | Research |
| Nc Sportz | Retail Trade | $51,200 | $20,531 | 5 | <$5M | Research |
| Mullenbach Funeral Homes LLC | Other Services (except Public Administration) | $44,272 | $44,591 | 6 | <$5M | Research |
| Dr David E Dibiase Pllc | Health Care and Social Assistance | $44,100 | $42,587 | 5 | <$5M | Research |
| Dr David E. Dibiase | Administrative and Support and Waste Management | $44,100 | $44,493 | 8 | <$5M | Research |
| Mullenbach Funeral Homes LLC | Other Services (except Public Administration) | $43,119 | $43,436 | 6 | <$5M | Research |
| Michael Pipo DBA None | Health Care and Social Assistance | $41,665 | $56,482 | 6 | <$5M | Research |
| Therapy Provider Services Organization | Health Care and Social Assistance | $40,000 | $52,276 | 5 | <$5M | Research |
| St. Anthony Church | Other Services (except Public Administration) | $31,505 | $31,754 | 11 | N/A | Research |
| Paramount Technologies, INC | Administrative and Support and Waste Management | $29,200 | $29,481 | 3 | <$5M | Research |
| Sarah Jahrell | Accommodation and Food Services | $28,933 | $0 | 1 | <$5M | Research |
| Jessica Vittek, Dvm, LLC | Professional, Scientific, and Technical Services | $27,700 | $27,865 | 8 | <$5M | Research |
| Paramount Technologies INC | Wholesale Trade | $27,680 | $28,117 | 3 | <$5M | Research |