| Wetzel County Hospital Association | Health Care and Social Assistance | $1,963,435 | $1,990,278 | 271 | N/A |  Research |
| Litman Excavating | Construction | $1,394,250 | $1,407,772 | 96 | $32.7M | Research |
| Litman Excavating | Construction | $1,394,250 | $1,411,974 | 81 | $27.6M | Research |
| New Martinsville Supply Co INC | Retail Trade | $492,200 | $495,107 | 69 | $14.2M | Research |
| Nelson Hachem | Unknown | $448,900 | $453,893 | 1 | N/A | Research |
| Sprouse Building Products, Inc. | Manufacturing | $393,275 | $396,378 | 44 | $10.8M | Research |
| Mjd, Inc. | Construction | $291,347 | $295,146 | 22 | $6.7M | Research |
| Lanam Foundry Corporation | Manufacturing | $237,500 | $0 | 2 | <$5M | Research |
| Wetzel-Valley Agencies Inc. | Real Estate and Rental and Leasing | $200,500 | $202,288 | 13 | <$5M | Research |
| Frank Hunt | Other Services (except Public Administration) | $173,185 | $174,779 | 14 | <$5M | Research |
| Wetzel County Emergency Ambulance Authority INC | Health Care and Social Assistance | $165,700 | $167,279 | 26 | N/A | Research |
| Wetzel County Emergency Ambulance Author | Health Care and Social Assistance | $165,700 | $166,975 | 26 | N/A | Research |
| Quinet's Court Restaurant Corp. | Accommodation and Food Services | $164,356 | $166,513 | 20 | <$5M | Research |
| J. C. Mensore, Distributor, Inc. | Wholesale Trade | $164,007 | $165,040 | 27 | $6.9M | Research |
| New Martinsville Wv 1213 LLC | Accommodation and Food Services | $147,974 | $148,931 | 17 | $5.3M | Research |
| Quinet's Court Restaurant Corp. | Accommodation and Food Services | $131,200 | $132,858 | 32 | $5.7M | Research |
| Prosite Business Solutions LLC | Professional, Scientific, and Technical Services | $128,148 | $128,767 | 5 | <$5M | Research |
| Dos Hermanos LLC | Agriculture, Forestry, Fishing and Hunting | $121,389 | $122,828 | 11 | <$5M | Research |
| Dos Hermanos INC | Agriculture, Forestry, Fishing and Hunting | $121,300 | $122,668 | 18 | <$5M | Research |
| Country Roads Ford INC | Retail Trade | $119,636 | $120,267 | 19 | <$5M | Research |
| Country Roads Ford INC | Retail Trade | $119,600 | $120,394 | 20 | $5.0M | Research |
| Bridge Street L.l.c. | Retail Trade | $111,470 | $112,408 | 18 | <$5M | Research |
| Legacy Investments, INC | Retail Trade | $105,800 | $106,620 | 22 | $5.5M | Research |
| New Martinsville, Wv 1213 LLC | Accommodation and Food Services | $102,500 | $103,188 | 18 | $5.6M | Research |
| Snyder & Hassig | Professional, Scientific, and Technical Services | $92,072 | $92,849 | 8 | <$5M | Research |