| Weather Shield Mfg., Inc. | Manufacturing | $9,426,774 | $9,535,505 | 500 | $495.9M | Research |
| James Peterson Sons, INC | Construction | $2,398,800 | $2,427,319 | 115 | $35.6M | Research |
| Medford Co-Operative, Inc. | Wholesale Trade | $1,106,243 | $1,113,187 | 170 | $43.8M | Research |
| J Bauer Trucking INC | Transportation and Warehousing | $912,200 | $919,903 | 77 | $15.5M | Research |
| Midwest Title Group, LLC | Real Estate and Rental and Leasing | $717,000 | $722,009 | 101 | $18.5M | Research |
| Enerquip, LLC | Manufacturing | $687,500 | $693,668 | 50 | $12.2M | Research |
| Prochnow Transport Inc. | Transportation and Warehousing | $646,500 | $652,121 | 57 | $11.5M | Research |
| Perry Arndt, O.d., S.c. | Health Care and Social Assistance | $537,300 | $216,218 | 23 | $5.4M | Research |
| Medford Motors, Inc. | Retail Trade | $497,200 | $500,570 | 35 | $8.8M | Research |
| Van Ansem Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $412,270 | $414,812 | 33 | $5.4M | Research |
| A&m Dittrich Mink Farm, Inc. | Agriculture, Forestry, Fishing and Hunting | $407,000 | $410,154 | 89 | $14.6M | Research |
| Mid-States Equipment | Wholesale Trade | $352,000 | $354,014 | 24 | $7.4M | Research |
| Commercial Recycling Corporation | Wholesale Trade | $314,000 | $315,840 | 36 | $11.0M | Research |
| Klinner Insurance, Inc. | Finance and Insurance | $298,600 | $300,284 | 21 | $10.8M | Research |
| Freudenthal Mfg., Inc. | Manufacturing | $275,000 | $276,894 | 20 | $5.2M | Research |
| Huotari Construction Inc. | Construction | $244,497 | $245,916 | 23 | $26.2M | Research |
| Huotari Construction Inc. | Construction | $244,200 | $245,570 | 18 | $20.5M | Research |
| Spectrum Benefit Solutions of Central Wisconsin, LLC | Finance and Insurance | $232,300 | $234,462 | 15 | $7.7M | Research |
| Perry Arndt Od Sc | Health Care and Social Assistance | $214,947 | $216,284 | 23 | $5.4M | Research |
| Medford Veterinary Clinic, S.c. | Professional, Scientific, and Technical Services | $204,000 | $205,343 | 19 | <$5M | Research |
| Hope Hospice and Palliative Care, Inc. | Health Care and Social Assistance | $181,000 | $182,141 | 25 | N/A | Research |
| Our Lady of the Holy Rosary Catholic Church | Other Services (except Public Administration) | $179,000 | $180,106 | 32 | N/A | Research |
| United Mutual Insurance Company | Finance and Insurance | $173,000 | $174,100 | 14 | $7.2M | Research |
| Wheelers Chevrolet of Medford, INC | Retail Trade | $159,105 | $160,913 | 19 | <$5M | Research |
| Brandner Dairy LLC | Agriculture, Forestry, Fishing and Hunting | $151,300 | $152,137 | 19 | <$5M | Research |