| Spooner Health System, Inc. | Health Care and Social Assistance | $2,015,300 | $2,037,938 | 150 | N/A |  Research |
| R Stresau Laboratory INC | Manufacturing | $825,000 | $832,402 | 83 | $21.7M | Research |
| David K & Ellen M Schmitz INC | Retail Trade | $708,900 | $715,639 | 151 | $37.7M | Research |
| T&t Manufacturing, LLC | Manufacturing | $695,739 | $665,849 | 64 | $16.8M | Research |
| Terry Leckel Trucking, Inc. | Transportation and Warehousing | $424,165 | $426,946 | 48 | $9.7M | Research |
| Penguindata Workforce Management Inc. | Information | $421,000 | $424,029 | 20 | <$5M | Research |
| Anderson Hager & Moe S.c. | Professional, Scientific, and Technical Services | $421,000 | $423,631 | 33 | $10.5M | Research |
| Cureium Healthcare Holdings, Inc. | Wholesale Trade | $260,400 | $263,800 | 22 | $5.7M | Research |
| Red Cross Pharmacy Inc. | Retail Trade | $226,200 | $227,752 | 36 | $6.3M | Research |
| Round Man Brewing Co. LLC | Accommodation and Food Services | $196,560 | $198,973 | 26 | <$5M | Research |
| Leiterman & Associates, INC | Manufacturing | $156,805 | $157,702 | 13 | <$5M | Research |
| Northland Hardware Company Inc. | Retail Trade | $155,000 | $155,906 | 47 | $9.7M | Research |
| Christopher S Carroll DDS PC | Health Care and Social Assistance | $142,740 | $143,811 | 15 | <$5M | Research |
| Christopher S. Carroll, D.d.s P.c | Health Care and Social Assistance | $142,500 | $143,551 | 16 | <$5M | Research |
| Round Man Brewing Co, | Accommodation and Food Services | $140,400 | $141,547 | 36 | $6.4M | Research |
| St Francis De Sales Catholic Church | Other Services (except Public Administration) | $121,500 | $122,637 | 20 | <$5M | Research |
| Tony's Riverside INC | Accommodation and Food Services | $112,996 | $113,806 | 12 | <$5M | Research |
| Fox Petroleum Company INC | Retail Trade | $104,173 | $104,928 | 14 | <$5M | Research |
| W-K Appliances, Inc. | Retail Trade | $102,815 | $103,539 | 17 | <$5M | Research |
| Paul Kloek | Health Care and Social Assistance | $99,747 | $100,088 | 10 | <$5M | Research |
| Olsen Enterprises of Spooner, Inc. | Accommodation and Food Services | $95,161 | $95,880 | 24 | <$5M | Research |
| Kloek Dentistry LLC | Health Care and Social Assistance | $91,437 | $92,219 | 9 | <$5M | Research |
| Precision Countertops, Inc. | Retail Trade | $87,700 | $88,342 | 8 | <$5M | Research |
| Spooner Physical Therapy & Wellness INC | Health Care and Social Assistance | $82,336 | $82,919 | 9 | <$5M | Research |
| Spooner Physical Therapy & Wellness, Inc. | Health Care and Social Assistance | $82,300 | $83,489 | 8 | <$5M | Research |