| West Park Hospital District | Health Care and Social Assistance | $5,540,238 | $5,587,443 | 402 | N/A |  Research |
| Quin Blair Enterprises INC | Accommodation and Food Services | $1,312,360 | $1,319,156 | 106 | $33.1M | Research |
| Tri County Telephone Association, INC | Information | $1,307,700 | $1,322,303 | 103 | $17.3M | Research |
| Buffalo Bill Memorial Association | Arts, Entertainment, and Recreation | $1,301,710 | $1,311,268 | 91 | N/A | Research |
| Buffalo Bill Memorial Association | Arts, Entertainment, and Recreation | $1,278,827 | $1,287,726 | 91 | N/A | Research |
| Quin Blair Enterprises INC | Accommodation and Food Services | $937,400 | $946,671 | 63 | $19.7M | Research |
| Gunwerks, LLC | Wholesale Trade | $818,707 | $824,494 | 52 | $15.9M | Research |
| R.t.j., Inc. | Accommodation and Food Services | $611,202 | $616,946 | 170 | $30.2M | Research |
| Cih INC | Accommodation and Food Services | $561,764 | $564,673 | 50 | $8.9M | Research |
| Engineering Associates | Professional, Scientific, and Technical Services | $535,000 | $538,488 | 36 | <$5M | Research |
| Harris Trucking & Construction Co | Construction | $442,900 | $445,606 | 34 | $10.5M | Research |
| Big Horn Basin Bone and Joint, LLC | Health Care and Social Assistance | $436,600 | $476,003 | 30 | $9.4M | Research |
| Choice Aviation LLC | Transportation and Warehousing | $433,100 | $435,746 | 49 | $12.4M | Research |
| Legend Communications of Wyoming, LLC | Information | $404,200 | $407,223 | 42 | $7.1M | Research |
| C.i.h., Inc. | Real Estate and Rental and Leasing | $401,260 | $406,119 | 52 | $9.5M | Research |
| Legend Communications Wy LLC | Information | $395,890 | $400,153 | 45 | $7.6M | Research |
| Titan Casing LLC | Mining, Quarrying, and Oil and Gas Extraction | $358,641 | $361,726 | 15 | <$5M | Research |
| Titan Casing LLC | Mining, Quarrying, and Oil and Gas Extraction | $358,641 | $361,707 | 9 | <$5M | Research |
| Sunset Properties Inc. | Accommodation and Food Services | $346,348 | $348,340 | 80 | $25.0M | Research |
| Bei Services, Inc. | Professional, Scientific, and Technical Services | $334,100 | $336,471 | 20 | <$5M | Research |
| Sbw & Associates PC | Professional, Scientific, and Technical Services | $332,262 | $335,057 | 19 | $6.0M | Research |
| Fremont Motor Cody, INC | Retail Trade | $316,900 | $318,995 | 28 | $7.1M | Research |
| Northern Wyoming Surgical Center, LLC | Health Care and Social Assistance | $315,800 | $325,014 | 20 | <$5M | Research |
| Rawhide Well Service LLC | Mining, Quarrying, and Oil and Gas Extraction | $302,182 | $303,124 | 20 | <$5M | Research |
| Wyoming Auto Investments LLC | Retail Trade | $295,600 | $297,285 | 27 | $6.8M | Research |