| Memorial Hospital of Converse County | Health Care and Social Assistance | $4,455,350 | $6,417,173 | 413 | N/A |  Research |
| R & R Services, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $3,139,600 | $3,176,415 | 137 | $8.3M | Research |
| Northwinds of Wyoming Inc. | Construction | $1,550,000 | $1,559,342 | 66 | $20.5M | Research |
| North Platte Physical Therapy Services, Inc. | Health Care and Social Assistance | $1,532,700 | $1,541,518 | 179 | $48.3M | Research |
| Northwinds of Wyoming, Inc. | Construction | $1,514,500 | $1,526,657 | 124 | $38.4M | Research |
| Igo Oil Field Service INC | Mining, Quarrying, and Oil and Gas Extraction | $1,206,700 | $1,216,354 | 65 | <$5M | Research |
| Igo Oil Field Service Inc. | Mining, Quarrying, and Oil and Gas Extraction | $1,206,700 | $1,211,791 | 41 | <$5M | Research |
| Miller Fabrication LLC | Construction | $961,623 | $966,270 | 46 | $14.3M | Research |
| Road Runner Service & Supply, LLC | Mining, Quarrying, and Oil and Gas Extraction | $652,600 | $658,214 | 36 | <$5M | Research |
| Jerry's Welding Service Inc. | Mining, Quarrying, and Oil and Gas Extraction | $523,327 | $526,381 | 24 | <$5M | Research |
| Jerry's Welding Service INC | Other Services (except Public Administration) | $523,300 | $526,210 | 30 | $6.4M | Research |
| Douglas Care Center, LLC | Health Care and Social Assistance | $464,100 | $460,887 | 69 | $11.7M | Research |
| Road Runner Service & Supply LLC | Mining, Quarrying, and Oil and Gas Extraction | $460,720 | $465,100 | 36 | <$5M | Research |
| Wagonhound Land & Livestock, LLC | Agriculture, Forestry, Fishing and Hunting | $431,700 | $434,196 | 37 | $6.1M | Research |
| K&r Operating, LLC | Mining, Quarrying, and Oil and Gas Extraction | $306,700 | $308,750 | 15 | <$5M | Research |
| Saratoga Care Center LLC | Health Care and Social Assistance | $259,400 | $262,236 | 36 | $6.1M | Research |
| Thunder Basin Orthopaedics and Sports Medicine PC | Health Care and Social Assistance | $243,595 | $245,544 | 25 | $7.8M | Research |
| Nutrition Center Incorporated | Manufacturing | $241,300 | $242,655 | 43 | $42.6M | Research |
| Braehead Lodging LLC | Accommodation and Food Services | $230,200 | $231,190 | 38 | $11.9M | Research |
| North Bill Disposal LLC | Administrative and Support and Waste Management | $222,600 | $223,527 | 12 | <$5M | Research |
| North Bill Disposal, LLC | Administrative and Support and Waste Management | $222,600 | $223,862 | 24 | <$5M | Research |
| Beg LLC | Retail Trade | $213,449 | $215,502 | 46 | $15.4M | Research |
| Beg, LLC | Unknown | $213,400 | $215,096 | 100 | N/A | Research |
| Douglas Exploration & Valley W | Mining, Quarrying, and Oil and Gas Extraction | $208,300 | $209,520 | 15 | <$5M | Research |
| Douglas Exploration & Valley W | Mining, Quarrying, and Oil and Gas Extraction | $207,300 | $209,453 | 14 | <$5M | Research |