| Powell Valley Healtch Care, Inc. | Health Care and Social Assistance | $5,040,506 | $5,099,335 | 449 | N/A |  Research |
| Children's Resource Center | Health Care and Social Assistance | $858,000 | $862,748 | 79 | N/A | Research |
| Kbla INC | Retail Trade | $680,100 | $686,156 | 120 | $30.0M | Research |
| Triple a Building Services, Inc. | Construction | $363,875 | $350,539 | 26 | $29.6M | Research |
| Dick Jones Trucking | Transportation and Warehousing | $331,613 | $333,457 | 20 | <$5M | Research |
| Dick Jones Trucking | Transportation and Warehousing | $331,613 | $333,702 | 17 | <$5M | Research |
| Fremont Motor Powell, LLC | Retail Trade | $261,800 | $263,531 | 27 | $6.8M | Research |
| Yellowstone Motors LLC | Retail Trade | $240,029 | $243,063 | 23 | $5.8M | Research |
| Whittle, Hamilton and Associates, P.c. | Professional, Scientific, and Technical Services | $195,282 | $196,347 | 15 | <$5M | Research |
| Trinity Teen Solutions INC | Health Care and Social Assistance | $187,853 | $189,515 | 17 | <$5M | Research |
| Powell Health Care Coalition | Health Care and Social Assistance | $185,200 | $187,270 | 20 | N/A | Research |
| Bar-T Electric, Inc. | Construction | $178,185 | $179,156 | 11 | <$5M | Research |
| Trinity Teen Solutions, Inc. | Health Care and Social Assistance | $172,875 | $173,935 | 20 | <$5M | Research |
| Pace Setters LLC | Transportation and Warehousing | $168,587 | $169,723 | 22 | $5.9M | Research |
| Johnson's Oil and Water Service, LLC | Mining, Quarrying, and Oil and Gas Extraction | $165,680 | $166,638 | 8 | <$5M | Research |
| Johnson's Oil and Water Service LLC | Transportation and Warehousing | $165,680 | $166,511 | 8 | <$5M | Research |
| Eastman's Publishing Inc. | Information | $165,148 | $166,265 | 12 | <$5M | Research |
| Eastman's Publishing INC | Information | $165,148 | $166,224 | 12 | <$5M | Research |
| Heart Mountain Farm Supply | Other Services (except Public Administration) | $154,500 | $155,372 | 12 | <$5M | Research |
| Northern Developmental Disability Service Providers, INC | Health Care and Social Assistance | $151,663 | $152,776 | 47 | $8.0M | Research |
| Rocky Mountain Recovery Systems INC | Unknown | $149,448 | $151,089 | 21 | N/A | Research |
| Wyoming Completion Technologies | Manufacturing | $147,673 | $148,733 | 10 | <$5M | Research |
| Wyoming Completion Technologie | Mining, Quarrying, and Oil and Gas Extraction | $147,600 | $148,532 | 17 | <$5M | Research |
| Heart Mountain Farm Supply | Other Services (except Public Administration) | $141,600 | $142,283 | 14 | <$5M | Research |
| Shoshone Valley Crop & Seed, Inc. | Agriculture, Forestry, Fishing and Hunting | $137,908 | $139,241 | 11 | <$5M | Research |