| Arkansas Valley Regional Medical Center | Health Care and Social Assistance | $3,788,100 | $3,830,963 | 293 | N/A |  Research |
| Lewis Bolt and Nut Company | Manufacturing | $3,101,910 | $3,134,911 | 276 | $77.1M | Research |
| Lewis Bolt & Nut Company | Manufacturing | $2,000,000 | $2,009,389 | 276 | $67.5M | Research |
| Arkansas Valley Regional Medical Center | Health Care and Social Assistance | $2,000,000 | $2,006,411 | 279 | N/A | Research |
| Southeast Colorado Power Association | Utilities | $1,043,454 | $1,054,460 | 48 | N/A | Research |
| Southeast Behavioral Health Group | Health Care and Social Assistance | $1,000,000 | $1,005,222 | 164 | N/A | Research |
| Secom, Inc. | Utilities | $963,810 | $970,992 | 61 | N/A | Research |
| Debourgh Manufacturing Company | Manufacturing | $910,367 | $915,425 | 107 | $28.0M | Research |
| Inspiration Field | Health Care and Social Assistance | $760,662 | $766,601 | 130 | $21.1M | Research |
| Oliver Manufacturing Company INC | Manufacturing | $582,420 | $585,510 | 41 | $10.7M | Research |
| Oliver Manufacturing Co., Inc. | Manufacturing | $582,400 | $586,331 | 45 | $11.8M | Research |
| Diamond a Farms, LLP | Agriculture, Forestry, Fishing and Hunting | $323,061 | $325,264 | 35 | <$5M | Research |
| Diamond a Farms G.p | Agriculture, Forestry, Fishing and Hunting | $320,550 | $322,008 | 25 | <$5M | Research |
| Wallace Oil Company | Wholesale Trade | $219,662 | $221,383 | 28 | $7.2M | Research |
| La Junta Livestock Commission, Inc. | Wholesale Trade | $200,000 | $201,928 | 47 | $12.1M | Research |
| Arkansas Valley Hospice INC | Health Care and Social Assistance | $194,572 | $195,837 | 19 | N/A | Research |
| Esjc INC | Manufacturing | $171,850 | $132,232 | 9 | <$5M | Research |
| Hirakata Farms LLC | Agriculture, Forestry, Fishing and Hunting | $165,055 | $165,968 | 96 | $9.8M | Research |
| Digitcom Electronicx, INC | Information | $154,238 | $155,099 | 13 | <$5M | Research |
| Digitcom Electronics Inc. | Manufacturing | $154,237 | $154,691 | 14 | <$5M | Research |
| Arkansas Valley Family Practice, Professional LLC | Health Care and Social Assistance | $147,800 | $149,642 | 16 | $5.0M | Research |
| Ballantyne Vision Care, LLC | Health Care and Social Assistance | $142,873 | $143,675 | 16 | <$5M | Research |
| Tri-County Gm, Inc. | Retail Trade | $120,976 | $121,778 | 25 | $6.3M | Research |
| Ad Tuck Inc. | Accommodation and Food Services | $108,942 | $109,484 | 11 | <$5M | Research |
| Fargerson LLC | Accommodation and Food Services | $106,046 | $106,732 | 9 | <$5M | Research |