| A & a Enterprise of La Junta | Accommodation and Food Services | $103,418 | $103,981 | 18 | $5.6M |  Research |
| Ruby's Auto Body Inc. | Retail Trade | $100,293 | $101,012 | 10 | <$5M | Research |
| Arkansas Valley Coop Assn. | Wholesale Trade | $97,500 | $98,139 | 14 | <$5M | Research |
| La Junta Ltc Investors LLC | Health Care and Social Assistance | $94,722 | $95,435 | 17 | <$5M | Research |
| Ryon Medical & Associates LLC | Health Care and Social Assistance | $94,608 | $95,241 | 18 | $5.6M | Research |
| Morgan & Sons Glass INC | Construction | $86,200 | $86,954 | 7 | <$5M | Research |
| La Junta Trading Company INC | Retail Trade | $84,959 | $85,764 | 15 | <$5M | Research |
| Prince Preferred Hotels, La Junta, LLC | Accommodation and Food Services | $84,405 | $85,399 | 23 | $7.2M | Research |
| Tri-County Collective Group | Retail Trade | $84,308 | $84,966 | 18 | <$5M | Research |
| Falcon Industries INC | Manufacturing | $78,984 | $79,418 | 6 | <$5M | Research |
| Falcon Industries INC | Manufacturing | $78,984 | $79,357 | 6 | <$5M | Research |
| Ad Tuck, Inc. | Accommodation and Food Services | $77,700 | $78,089 | 17 | <$5M | Research |
| Boss Hoggs Saloon & Restaurant | Accommodation and Food Services | $75,749 | $76,220 | 6 | <$5M | Research |
| A&a Enterprise of La Junta, INC | Accommodation and Food Services | $72,205 | $72,692 | 19 | $5.9M | Research |
| Opera House Pharmacy Co | Retail Trade | $66,457 | $66,952 | 7 | <$5M | Research |
| Colorado Veterinary Clinic, PC | Professional, Scientific, and Technical Services | $61,000 | $61,354 | 6 | <$5M | Research |
| David N Trujillo DDS PC | Health Care and Social Assistance | $60,748 | $61,177 | 12 | <$5M | Research |
| Ark Valley Animal Hospital | Professional, Scientific, and Technical Services | $53,400 | $53,732 | 7 | <$5M | Research |
| Valley Plumbing & Heating INC | Other Services (except Public Administration) | $51,807 | $52,260 | 5 | <$5M | Research |
| Gary Hanagan | Agriculture, Forestry, Fishing and Hunting | $49,513 | $49,701 | 5 | <$5M | Research |
| Best Bet Beeflot | Agriculture, Forestry, Fishing and Hunting | $47,841 | $47,994 | 7 | <$5M | Research |
| Best Bet Beeflot, Inc. | Agriculture, Forestry, Fishing and Hunting | $47,840 | $48,072 | 7 | <$5M | Research |
| Autocare On Site LLC | Other Services (except Public Administration) | $45,980 | $46,267 | 3 | <$5M | Research |
| Gsk Refrigeration | Construction | $45,382 | $20,995 | 1 | <$5M | Research |
| Down to Earth Dentistry LLC | Professional, Scientific, and Technical Services | $44,900 | $45,190 | 4 | <$5M | Research |