| Xavier High School Corporation of Middletown | Educational Services | $1,153,800 | $1,166,697 | 120 | N/A | AI Deep Dive |
| Change Incorporated | Health Care and Social Assistance | $1,132,300 | $1,148,939 | 300 | $48.6M | AI Deep Dive |
| Orthopedic Associates of Middletown, PC | Health Care and Social Assistance | $1,130,700 | $1,144,206 | 72 | $12.8M | AI Deep Dive |
| Xse Group INC | Wholesale Trade | $1,117,992 | $1,134,471 | 109 | $28.1M | AI Deep Dive |
| Xse Group INC | Professional, Scientific, and Technical Services | $1,117,992 | $1,142,190 | 99 | $13.9M | AI Deep Dive |
| Marc Community Resources, Ltd. | Health Care and Social Assistance | $1,026,700 | $1,035,223 | 134 | N/A | AI Deep Dive |
| Greenskies Clean Energy LLC | Utilities | $1,013,600 | $1,022,875 | 71 | N/A | AI Deep Dive |
| Mercy High School Corporation | Educational Services | $953,517 | $958,768 | 63 | N/A | AI Deep Dive |
| Nissan of Middletown Ct, LLC | Retail Trade | $949,500 | $962,160 | 86 | $21.7M | AI Deep Dive |
| New England Residential Services | Health Care and Social Assistance | $949,100 | $958,799 | 118 | $20.2M | AI Deep Dive |
| Aerospace Techniques INC | Manufacturing | $942,360 | $951,345 | 80 | $20.9M | AI Deep Dive |
| Pavilion Catering Inc. | Accommodation and Food Services | $926,440 | $934,315 | 134 | $25.0M | AI Deep Dive |
| Eol Packaging Experts | Manufacturing | $871,300 | $877,569 | 47 | $12.3M | AI Deep Dive |
| Mercy High School Corporation | Educational Services | $836,935 | $839,985 | 69 | N/A | AI Deep Dive |
| Kronenberger and Sons Restoration, Inc. | Construction | $823,500 | $830,494 | 46 | $52.4M | AI Deep Dive |
| Armani Restoration INC | Construction | $802,637 | $810,173 | 23 | $7.1M | AI Deep Dive |
| Norpaco, INC | Manufacturing | $791,909 | $796,313 | 93 | $32.8M | AI Deep Dive |
| Pnt Data Corp. | Professional, Scientific, and Technical Services | $786,612 | $796,245 | 37 | <$5M | AI Deep Dive |
| Pnt Data Corp. | Information | $786,612 | $791,590 | 37 | $6.2M | AI Deep Dive |
| Middlesex Gastroenterology Associates, LLC | Health Care and Social Assistance | $732,200 | $739,075 | 73 | $22.9M | AI Deep Dive |
| Connecticut Oncology Group, P.c. | Health Care and Social Assistance | $711,767 | $718,568 | 36 | $11.3M | AI Deep Dive |
| Radiologic Associates of Middletown PC | Health Care and Social Assistance | $701,655 | $711,055 | 31 | $9.7M | AI Deep Dive |
| Best Cleaners INC | Other Services (except Public Administration) | $681,622 | $688,760 | 135 | $25.8M | AI Deep Dive |
| Best Cleaners Inc. | Other Services (except Public Administration) | $681,600 | $689,912 | 130 | $24.8M | AI Deep Dive |
| Pavilion Catering, Inc. | Accommodation and Food Services | $629,170 | $468,523 | 94 | $17.5M | AI Deep Dive |