| Mahoney LLC | Other Services (except Public Administration) | $612,755 | $0 | 32 | $6.1M | Research |
| Prototype & Plastic Mold Company | Manufacturing | $591,225 | $597,818 | 49 | $12.8M | Research |
| Ymca of Northern Middlesex County, Inc. | Arts, Entertainment, and Recreation | $588,700 | $594,293 | 97 | N/A | Research |
| Phasor Engineering Services LLC | Professional, Scientific, and Technical Services | $575,345 | $579,500 | 31 | <$5M | Research |
| Reality Interactive, LLC | Professional, Scientific, and Technical Services | $563,747 | $570,105 | 44 | $9.1M | Research |
| Middlesex Cener for Advanced Orthopedic Surgery, LLC | Health Care and Social Assistance | $562,500 | $567,531 | 40 | $7.1M | Research |
| Fm Middletown Hospitality LLC | Accommodation and Food Services | $546,406 | $484,453 | 45 | $14.1M | Research |
| Phasor Engineering Services, LLC | Professional, Scientific, and Technical Services | $541,700 | $548,155 | 32 | <$5M | Research |
| Ymca of Northern Middlesex County Inc. | Other Services (except Public Administration) | $536,138 | $542,199 | 120 | N/A | Research |
| Mazzotta Rentals, Inc. | Real Estate and Rental and Leasing | $518,053 | $522,865 | 33 | $14.9M | Research |
| Key Acquisitions, LLC | Unknown | $517,400 | $522,772 | 40 | N/A | Research |
| Middlesex Eye Physicians PC | Health Care and Social Assistance | $515,217 | $518,523 | 35 | $11.0M | Research |
| Middlesex Eye Physician PC | Health Care and Social Assistance | $515,200 | $520,080 | 35 | $11.0M | Research |
| Armani Restoration, Inc. | Construction | $507,300 | $676,861 | 29 | $9.0M | Research |
| Tinny Corporation | Manufacturing | $501,500 | $508,298 | 48 | $13.4M | Research |
| Suburban Stationers Inc. | Retail Trade | $492,456 | $497,203 | 35 | $8.4M | Research |
| Plastic Design International, Inc. | Manufacturing | $463,968 | $466,599 | 41 | $40.7M | Research |
| Radiologic Associates of Middletown PC | Health Care and Social Assistance | $463,962 | $468,360 | 32 | $10.0M | Research |
| Guilmartin Dipiro & Sokolowski LLC | Professional, Scientific, and Technical Services | $437,000 | $440,654 | 24 | $7.6M | Research |
| East Coast Wall System, LLC | Construction | $426,003 | $429,316 | 30 | $6.9M | Research |
| Charles It, LLC | Other Services (except Public Administration) | $423,053 | $425,475 | 34 | $6.7M | Research |
| Crescent Street Obstetrics & Gynecology, LLC | Health Care and Social Assistance | $416,473 | $419,423 | 32 | $10.0M | Research |
| Connecticut Eye Physicians, P.c. | Health Care and Social Assistance | $412,971 | $418,764 | 11 | <$5M | Research |
| Bull Metal Products Co INC | Manufacturing | $406,895 | $322,393 | 37 | $9.0M | Research |
| Bishop's Auto Parts, Inc. | Retail Trade | $404,200 | $407,164 | 39 | $10.5M | Research |