| Suncoast Community Health Centers, INC | Health Care and Social Assistance | $4,746,700 | $4,800,669 | 426 | N/A |  Research |
| Enprovera Corporation | Professional, Scientific, and Technical Services | $2,678,468 | $2,708,261 | 165 | $17.1M | Research |
| Cyprexx Services, LLC | Other Services (except Public Administration) | $2,346,722 | $2,375,600 | 191 | $36.5M | Research |
| Cyprexx Services LLC | Construction | $2,000,000 | $2,014,556 | 173 | $58.9M | Research |
| Bay Area Cardiology Associates, P.a. | Health Care and Social Assistance | $1,975,000 | $1,761,942 | 105 | $33.0M | Research |
| Preferred Touch Home Care, Inc. | Health Care and Social Assistance | $1,790,492 | $1,810,525 | 241 | $41.3M | Research |
| Eks Group LLC | Professional, Scientific, and Technical Services | $1,651,075 | $1,675,638 | 374 | $38.7M | Research |
| Eks Group LLC | Professional, Scientific, and Technical Services | $1,566,663 | $1,577,394 | 143 | $20.0M | Research |
| Orthopaedic Medical Group of Tampa Bay PA | Health Care and Social Assistance | $1,321,300 | $1,328,069 | 116 | $36.4M | Research |
| Second Florida Living Options, LLC | Health Care and Social Assistance | $1,280,752 | $1,292,136 | 185 | $31.5M | Research |
| Second Florida Living Options LLC | Health Care and Social Assistance | $1,192,493 | $1,196,898 | 126 | $21.4M | Research |
| Bell Shoals Baptist Church of Brandon, Inc. | Other Services (except Public Administration) | $1,125,066 | $1,133,481 | 227 | N/A | Research |
| Beth Ingram & Associates, Inc. | Health Care and Social Assistance | $1,120,000 | $1,079,742 | 120 | $32.4M | Research |
| Phoenix Programs of Florida Inc. | Health Care and Social Assistance | $1,006,665 | $1,010,388 | 77 | N/A | Research |
| Phoenix Programs of Florida, Inc. | Health Care and Social Assistance | $991,700 | $996,998 | 96 | N/A | Research |
| Navigator Academy of Leadership, INC | Educational Services | $915,613 | $925,913 | 111 | N/A | Research |
| Gregory L. Henderson, M.d., F.a.c.s., Inc. | Health Care and Social Assistance | $882,000 | $890,183 | 103 | $32.3M | Research |
| Reemployability, Inc. | Administrative and Support and Waste Management | $803,065 | $810,159 | 60 | $9.4M | Research |
| Tampa Obstetrics PA | Health Care and Social Assistance | $773,000 | $777,320 | 33 | $10.4M | Research |
| Nativity Catholic School | Other Services (except Public Administration) | $698,020 | $705,795 | 77 | N/A | Research |
| Phil Mook Enterprises, Inc. | Professional, Scientific, and Technical Services | $694,000 | $699,286 | 217 | $22.5M | Research |
| Brandon Eye Associates, P.a. | Health Care and Social Assistance | $652,500 | $656,630 | 60 | $14.1M | Research |
| Exodus Women's Center, Inc. | Health Care and Social Assistance | $594,300 | $597,524 | 71 | $22.3M | Research |
| Cornerstone Medical Care of Brandon Pl | Health Care and Social Assistance | $589,340 | $593,909 | 58 | $18.2M | Research |
| Kobe of Brandon LLC | Accommodation and Food Services | $582,895 | $589,663 | 61 | $10.8M | Research |