| Chambers Medical Group Psc | Health Care and Social Assistance | $368,794 | $371,498 | 47 | $14.8M | AI Deep Dive |
| Church of the Nativity | Other Services (except Public Administration) | $364,539 | $368,660 | 33 | N/A | AI Deep Dive |
| Brandon Dermatology, P.a. | Health Care and Social Assistance | $360,800 | $312,777 | 51 | $16.0M | AI Deep Dive |
| Summit Eye Care, Pllc | Health Care and Social Assistance | $350,000 | $66,928 | 13 | <$5M | AI Deep Dive |
| Chambers Medical Group P.s.c. | Health Care and Social Assistance | $341,737 | $344,148 | 27 | $8.5M | AI Deep Dive |
| Payroll Only, INC | Professional, Scientific, and Technical Services | $337,500 | $16,914 | 135 | $43.0M | AI Deep Dive |
| Palmetto Veterinary Oncology, Inc. | Professional, Scientific, and Technical Services | $337,119 | $340,827 | 23 | <$5M | AI Deep Dive |
| Brandon Academy, LLC | Educational Services | $337,000 | $338,985 | 35 | <$5M | AI Deep Dive |
| Electric Today INC | Construction | $335,231 | $337,494 | 33 | $10.9M | AI Deep Dive |
| Divine Designs Salon & Spa Inc. | Other Services (except Public Administration) | $333,270 | $335,260 | 45 | $8.6M | AI Deep Dive |
| Brandon Sports and Aquatic Center, INC | Arts, Entertainment, and Recreation | $318,187 | $321,351 | 110 | N/A | AI Deep Dive |
| Brandon Sports and Aquatic Center INC | Arts, Entertainment, and Recreation | $318,080 | $321,609 | 100 | N/A | AI Deep Dive |
| Trevcon Enterprises | Retail Trade | $309,700 | $311,957 | 84 | $25.4M | AI Deep Dive |
| Curry Law Group PA | Professional, Scientific, and Technical Services | $309,000 | $312,519 | 19 | <$5M | AI Deep Dive |
| Stonewood Brandon LLC | Accommodation and Food Services | $307,931 | $309,770 | 40 | $7.1M | AI Deep Dive |
| Golden Slumbers INC | Accommodation and Food Services | $307,587 | $310,142 | 65 | $11.5M | AI Deep Dive |
| Jcss Jmc LLC | Accommodation and Food Services | $307,405 | $309,847 | 56 | $9.9M | AI Deep Dive |
| Boohoff Law, P.a. | Professional, Scientific, and Technical Services | $299,800 | $303,697 | 25 | $6.1M | AI Deep Dive |
| Jesse's Tavern | Accommodation and Food Services | $298,060 | $301,465 | 37 | $6.6M | AI Deep Dive |
| Pulmonary Associates of Brandon, PA | Health Care and Social Assistance | $291,100 | $293,947 | 33 | $10.4M | AI Deep Dive |
| On-Line Electric Service LLC | Construction | $280,180 | $282,989 | 60 | $19.7M | AI Deep Dive |
| 2025 Brandon Restaurant Corp | Accommodation and Food Services | $278,925 | $280,595 | 42 | $7.5M | AI Deep Dive |
| Black Rock Brandon LLC | Accommodation and Food Services | $277,400 | $281,124 | 47 | $8.3M | AI Deep Dive |
| US Solar Squared LLC | Professional, Scientific, and Technical Services | $276,742 | $278,819 | 16 | <$5M | AI Deep Dive |
| Jose Prieto, M.d., P.a. | Health Care and Social Assistance | $276,675 | $283,223 | 14 | <$5M | AI Deep Dive |