| Sfv-Llgc LLC | Construction | $394,500 | $399,450 | 30 | $34.2M |  Research |
| Ocean Church, Inc. | Other Services (except Public Administration) | $368,915 | $372,696 | 91 | N/A | Research |
| Jr Evans Engineering, P.a. | Professional, Scientific, and Technical Services | $362,693 | $365,634 | 23 | <$5M | Research |
| Jds of Coconut Point, Inc. | Accommodation and Food Services | $360,609 | $362,432 | 48 | $8.5M | Research |
| Estero Animal Hospital | Professional, Scientific, and Technical Services | $347,290 | $350,483 | 37 | $5.2M | Research |
| Gulf Coast Crunch, INC | Unknown | $334,760 | $337,795 | 95 | N/A | Research |
| Copperleaf Golf Club Community Assoc | Arts, Entertainment, and Recreation | $330,465 | $334,313 | 92 | $12.9M | Research |
| Alliance Packing LLC | Agriculture, Forestry, Fishing and Hunting | $315,543 | $318,733 | 30 | <$5M | Research |
| Nelmatt LLC | Accommodation and Food Services | $304,748 | $307,495 | 28 | <$5M | Research |
| Ladybug Farms INC | Agriculture, Forestry, Fishing and Hunting | $293,116 | $295,027 | 38 | <$5M | Research |
| Jag Building Group Inc. | Construction | $289,280 | $222,734 | 19 | $21.6M | Research |
| The Diamond District LLC | Retail Trade | $286,360 | $289,701 | 23 | $6.4M | Research |
| The Diamond District | Retail Trade | $276,476 | $279,010 | 22 | $6.1M | Research |
| Jds of Coconut Point, Inc. | Unknown | $257,450 | $259,728 | 41 | N/A | Research |
| Chops City Grill Bonita INC | Accommodation and Food Services | $255,913 | $259,069 | 20 | <$5M | Research |
| Leecorp Homes, Inc. | Retail Trade | $253,369 | $256,556 | 17 | <$5M | Research |
| Estero Dermatology & Skin Surgery Center LLC | Health Care and Social Assistance | $243,289 | $246,532 | 20 | $6.3M | Research |
| Everblades Food Services LLC | Accommodation and Food Services | $241,415 | $244,252 | 76 | $14.2M | Research |
| Cws at Gateway, Inc. | Health Care and Social Assistance | $223,000 | $225,364 | 40 | $6.5M | Research |
| The Villages at Country Creek | Arts, Entertainment, and Recreation | $213,800 | $215,255 | 25 | <$5M | Research |
| Tru Icons Management LLC | Management of Companies and Enterprises | $212,500 | $0 | 30 | <$5M | Research |
| Naturipe Farms Imports, Inc. | Wholesale Trade | $204,600 | $206,532 | 12 | <$5M | Research |
| Cary Hospitality LLC | Accommodation and Food Services | $202,683 | $203,866 | 38 | $11.9M | Research |
| Cws at Gateway Inc. | Health Care and Social Assistance | $202,228 | $203,840 | 30 | <$5M | Research |
| Naples Flatbread Estero LLC | Accommodation and Food Services | $201,143 | $202,626 | 34 | $6.0M | Research |