| St Paul's Catholic School | Educational Services | $583,365 | $589,263 | 108 | $13.0M |  Research |
| 24/7 Pediatric Care Centers, Inc. | Health Care and Social Assistance | $550,900 | $554,100 | 68 | $21.3M | Research |
| Beaches Recovery Services LLC | Health Care and Social Assistance | $546,500 | $550,538 | 45 | $8.0M | Research |
| Goruck Holdings LLC | Manufacturing | $544,200 | $485,912 | 24 | $8.5M | Research |
| Cortello Salon Inc. | Other Services (except Public Administration) | $518,161 | $517,046 | 52 | $9.9M | Research |
| Florida Restaurant Group LLC | Accommodation and Food Services | $514,699 | $518,337 | 71 | $12.6M | Research |
| Gotsoccer LLC | Information | $511,765 | $515,802 | 33 | $5.5M | Research |
| Cortello Salon INC | Other Services (except Public Administration) | $508,340 | $515,081 | 29 | $5.5M | Research |
| Works of B&l LLC | Accommodation and Food Services | $501,466 | $289,301 | 65 | $8.0M | Research |
| Veloce Pizzeria Napoletana, LLC | Accommodation and Food Services | $487,750 | $492,938 | 81 | $14.4M | Research |
| Print Reach, INC | Information | $441,179 | $443,813 | 29 | <$5M | Research |
| Moffitt Corporation, Inc. | Wholesale Trade | $437,520 | $442,479 | 21 | $6.4M | Research |
| Sweat Pt LLC | Other Services (except Public Administration) | $437,200 | $209,066 | 85 | $16.2M | Research |
| The Boat Company Ltd | Administrative and Support and Waste Management | $436,458 | $441,767 | 25 | N/A | Research |
| Swindell Bohn Durden & Phillips Pl | Professional, Scientific, and Technical Services | $425,300 | $428,306 | 26 | $8.3M | Research |
| Lynch's Irish Pub INC | Accommodation and Food Services | $419,767 | $423,312 | 38 | <$5M | Research |
| Discovery School of Jacksonville Inc, Th | Educational Services | $413,973 | $409,593 | 51 | N/A | Research |
| Operation New Hope, Inc. | Health Care and Social Assistance | $410,900 | $411,715 | 38 | N/A | Research |
| The Discovery School of Jacksonville in E | Educational Services | $406,155 | $408,692 | 48 | N/A | Research |
| Newport Jacksonville Beach Management LLC | Accommodation and Food Services | $403,200 | $407,355 | 57 | $17.8M | Research |
| Skiltrek LLC | Educational Services | $385,206 | $387,686 | 20 | <$5M | Research |
| Dockside Seafood Restaurant LLC | Accommodation and Food Services | $385,200 | $388,894 | 56 | $9.9M | Research |
| Swindell Bohn Durden & Phillips Pl | Professional, Scientific, and Technical Services | $377,800 | $381,713 | 20 | $6.4M | Research |
| Eleven South Inc. | Accommodation and Food Services | $374,600 | $377,295 | 45 | $8.0M | Research |
| Hashrocket, Inc. | Professional, Scientific, and Technical Services | $370,494 | $376,239 | 18 | <$5M | Research |