| T-Shirt City/sunglass City LLC | Retail Trade | $358,075 | $360,920 | 57 | $17.2M | AI Deep Dive |
| Protech E2, Inc. | Retail Trade | $347,500 | $351,332 | 42 | $12.9M | AI Deep Dive |
| Ham-Hark, Inc. | Accommodation and Food Services | $346,422 | $348,645 | 45 | $8.0M | AI Deep Dive |
| South Florida First Responders LLC | Construction | $341,395 | $346,404 | 20 | $22.8M | AI Deep Dive |
| Impact Windows Group LLC | Construction | $334,932 | $338,694 | 39 | $12.3M | AI Deep Dive |
| Rapid Emergency Deployment LLC | Utilities | $331,455 | $0 | 12 | N/A | AI Deep Dive |
| Hometown Bar-B-Q, LLC | Accommodation and Food Services | $323,404 | $326,168 | 35 | $6.2M | AI Deep Dive |
| Ted Carter Enterprises, INC | Administrative and Support and Waste Management | $319,667 | $322,642 | 30 | $5.7M | AI Deep Dive |
| Dolphins Plus Bayside Inc. | Professional, Scientific, and Technical Services | $301,800 | $304,550 | 33 | $6.9M | AI Deep Dive |
| Sebastian (kp) Enterprises INC | Administrative and Support and Waste Management | $300,000 | $301,625 | 33 | $7.1M | AI Deep Dive |
| J. A. Larocco Enterprises, Inc. | Construction | $296,000 | $299,322 | 46 | $10.6M | AI Deep Dive |
| The Galley of Key Largo Inc. | Accommodation and Food Services | $293,440 | $295,510 | 45 | $8.0M | AI Deep Dive |
| All Keys Concrete LLC | Construction | $291,872 | $295,147 | 36 | $8.3M | AI Deep Dive |
| Lazy Lobster LLC | Accommodation and Food Services | $287,500 | $291,485 | 45 | $8.0M | AI Deep Dive |
| Marine Resources Development Foundation INC | Accommodation and Food Services | $281,267 | $283,228 | 25 | $7.8M | AI Deep Dive |
| Cafe Largo, Inc. | Accommodation and Food Services | $272,960 | $276,046 | 70 | $12.4M | AI Deep Dive |
| Upper Keys Marine Construction LLC | Construction | $263,872 | $267,178 | 26 | $8.1M | AI Deep Dive |
| Jupiter Life Science Consulting, LLC | Professional, Scientific, and Technical Services | $254,127 | $257,254 | 12 | <$5M | AI Deep Dive |
| Sievers Marine Inc. | Accommodation and Food Services | $253,186 | $255,591 | 36 | $6.4M | AI Deep Dive |
| Sinclair Industries LLC | Accommodation and Food Services | $250,870 | $252,918 | 25 | <$5M | AI Deep Dive |
| Sievers Marine, Inc. | Accommodation and Food Services | $239,880 | $210,375 | 36 | $6.4M | AI Deep Dive |
| Seaway Plumbing, Inc. | Construction | $234,525 | $237,085 | 25 | $7.9M | AI Deep Dive |
| Pacifica Key Largo LP | Accommodation and Food Services | $234,461 | $236,446 | 37 | $11.6M | AI Deep Dive |
| Hometown Bar-B-Q, LLC | Accommodation and Food Services | $231,003 | $233,148 | 67 | $11.9M | AI Deep Dive |
| Kli Shell Lumber & Hardware, LLC | Retail Trade | $225,965 | $230,685 | 28 | $5.8M | AI Deep Dive |