| Landscape Products INC | Administrative and Support and Waste Management | $300,000 | $303,633 | 30 | $6.5M | Research |
| Coco Sod Farms Inc. | Administrative and Support and Waste Management | $289,768 | $291,832 | 56 | $12.1M | Research |
| Family Tree Enterprises Limited Partnership Lllp | Agriculture, Forestry, Fishing and Hunting | $287,300 | $289,487 | 49 | $8.0M | Research |
| Eli's Western Wear, INC | Retail Trade | $273,328 | $274,921 | 45 | $13.6M | Research |
| Coco Sod Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $260,768 | $262,333 | 30 | <$5M | Research |
| Yellowfins Vii LLC | Accommodation and Food Services | $255,500 | $257,721 | 68 | $12.1M | Research |
| Okeechobee Livestock Market INC | Agriculture, Forestry, Fishing and Hunting | $240,000 | $242,800 | 43 | $7.0M | Research |
| J. A. Wilcox, Inc. | Construction | $232,000 | $234,874 | 19 | $5.8M | Research |
| C & M Rucks Dairy, Inc. | Agriculture, Forestry, Fishing and Hunting | $228,800 | $230,503 | 23 | <$5M | Research |
| Jl Partners, LLC | Arts, Entertainment, and Recreation | $225,500 | $227,580 | 28 | <$5M | Research |
| Beck Construction LLC | Construction | $224,008 | $226,048 | 15 | <$5M | Research |
| Atland Recycling INC | Construction | $223,700 | $131,566 | 14 | <$5M | Research |
| Dunklin Memorial Church, Inc. | Other Services (except Public Administration) | $223,443 | $201,044 | 42 | N/A | Research |
| Total Roadside Services, LLC | Administrative and Support and Waste Management | $218,000 | $220,743 | 25 | <$5M | Research |
| Total Roadside Services LLC | Other Services (except Public Administration) | $217,985 | $221,055 | 27 | $5.3M | Research |
| Milking R INC | Agriculture, Forestry, Fishing and Hunting | $217,600 | $219,955 | 25 | <$5M | Research |
| New American Physical Therapy INC | Health Care and Social Assistance | $201,545 | $203,830 | 20 | $5.4M | Research |
| Willaway Cattle Company, INC | Agriculture, Forestry, Fishing and Hunting | $190,500 | $192,786 | 17 | <$5M | Research |
| Yellowfins Vii, LLC | Accommodation and Food Services | $182,000 | $183,441 | 58 | $10.3M | Research |
| Okeechobee Christian Academy INC | Educational Services | $176,900 | $178,669 | 41 | N/A | Research |
| Muhammad K. Syed MD P.a. | Health Care and Social Assistance | $174,800 | $177,496 | 20 | $6.3M | Research |
| Muhammad K Syed MD P.a. | Health Care and Social Assistance | $174,800 | $175,782 | 19 | $6.0M | Research |
| Okeechobee Veterinary Hospital Inc. | Professional, Scientific, and Technical Services | $174,706 | $176,783 | 24 | <$5M | Research |
| Pogey's Inc. | Accommodation and Food Services | $174,470 | $176,989 | 24 | <$5M | Research |
| Gator Security, Inc. | Manufacturing | $167,500 | $169,417 | 17 | <$5M | Research |