| St. Lucie Draft House & Sports Bar Inc. | Accommodation and Food Services | $273,400 | $276,568 | 19 | <$5M |  Research |
| Vacation Superstore Network, Inc. | Administrative and Support and Waste Management | $269,600 | $272,902 | 28 | $8.9M | Research |
| Miranda Plumbing & Air Conditioning, Inc. | Construction | $265,500 | $266,982 | 22 | $7.0M | Research |
| Sparks & Sparks LLC | Accommodation and Food Services | $262,740 | $264,638 | 25 | <$5M | Research |
| D & D Garage Doors of Port St. Lucie. Inc. | Construction | $262,113 | $265,491 | 31 | $5.3M | Research |
| Florida Metrology, LLC | Professional, Scientific, and Technical Services | $260,627 | $263,103 | 15 | <$5M | Research |
| Apex Billing LLC | Professional, Scientific, and Technical Services | $260,413 | $265,564 | 26 | <$5M | Research |
| Idproductsource LLC | Transportation and Warehousing | $259,232 | $206,880 | 28 | <$5M | Research |
| Mck Veranda Falls LLC | Accommodation and Food Services | $253,200 | $255,912 | 39 | $6.9M | Research |
| Tradition Surgery Center, LLC | Health Care and Social Assistance | $243,362 | $246,215 | 18 | <$5M | Research |
| Valant Associates LLC | Health Care and Social Assistance | $242,185 | $188,159 | 17 | $5.3M | Research |
| Surgcenter of St. Lucie, LLC | Health Care and Social Assistance | $235,547 | $238,257 | 39 | $6.9M | Research |
| Hokkaido Hibachi & Sushi, LLC | Accommodation and Food Services | $234,500 | $236,428 | 34 | $6.0M | Research |
| Ess Manufacturing INC | Manufacturing | $234,250 | $236,374 | 39 | $9.5M | Research |
| Gulfstream Urology Associates, P.a. | Health Care and Social Assistance | $227,100 | $99,695 | 7 | <$5M | Research |
| Bledsoe Enterprises LLC | Transportation and Warehousing | $221,155 | $222,464 | 33 | $8.2M | Research |
| Barnabei Investment Group LLC | Accommodation and Food Services | $220,899 | $222,273 | 30 | $5.3M | Research |
| Sunny Communications, Inc. | Information | $214,430 | $207,416 | 25 | <$5M | Research |
| Bbl Equinox at Tradition, LLC | Accommodation and Food Services | $213,862 | $216,553 | 37 | $11.6M | Research |
| Engineering Design & Construction, Inc. | Professional, Scientific, and Technical Services | $210,900 | $417,027 | 28 | <$5M | Research |
| Stranigan, Askeland & Harris Dmd's PA | Health Care and Social Assistance | $203,900 | $205,118 | 19 | <$5M | Research |
| Aero Engine Solutions INC | Manufacturing | $200,533 | $203,137 | 15 | <$5M | Research |
| Sparkle M&m, LLC | Other Services (except Public Administration) | $200,277 | $202,563 | 29 | $5.7M | Research |
| Questcomm INC | Information | $198,034 | $199,536 | 25 | <$5M | Research |
| Quest Comm Inc. | Information | $198,034 | $199,358 | 21 | <$5M | Research |