| Georgia Forest Products, Inc. | Agriculture, Forestry, Fishing and Hunting | $309,760 | $311,534 | 29 | <$5M |  Research |
| Sumter Pediatrics, LLC | Health Care and Social Assistance | $298,190 | $301,810 | 31 | $9.7M | Research |
| Council Services INC | Health Care and Social Assistance | $294,900 | $296,904 | 78 | $12.6M | Research |
| M & D Masonry, Inc. | Construction | $287,992 | $289,705 | 26 | <$5M | Research |
| Innovative Senior Solutions, LLC | Health Care and Social Assistance | $287,900 | $289,987 | 35 | $6.0M | Research |
| Innovative Senior Solutions, LLC | Health Care and Social Assistance | $286,976 | $288,808 | 31 | $5.0M | Research |
| Regional Eye Center, LLP | Health Care and Social Assistance | $279,427 | $377,962 | 70 | $16.4M | Research |
| Shiver Lumber Company, Inc. | Wholesale Trade | $278,360 | $279,927 | 39 | $11.9M | Research |
| Windsor Hotel Americus, Inc. | Accommodation and Food Services | $267,812 | $270,336 | 35 | $10.9M | Research |
| Sunbelt Ford of Americus INC | Retail Trade | $255,200 | $257,549 | 25 | $6.3M | Research |
| Southeastern Sod, Inc. | Agriculture, Forestry, Fishing and Hunting | $248,568 | $250,086 | 32 | <$5M | Research |
| Perry Wellness Center Inc. | Health Care and Social Assistance | $236,127 | $238,080 | 42 | $7.5M | Research |
| West Logging INC | Agriculture, Forestry, Fishing and Hunting | $232,860 | $234,474 | 16 | <$5M | Research |
| Container Marketing, Inc. | Manufacturing | $229,265 | $217,412 | 47 | $12.3M | Research |
| Social Exchange | Health Care and Social Assistance | $229,168 | $0 | 18 | <$5M | Research |
| Reid Bros. Irrigation | Wholesale Trade | $224,776 | $226,414 | 22 | $6.7M | Research |
| Perry Brothers Logistics, Incorporated | Real Estate and Rental and Leasing | $220,540 | $222,195 | 16 | <$5M | Research |
| Automation & Control Systems, Inc. | Other Services (except Public Administration) | $215,261 | $95,217 | 8 | <$5M | Research |
| Machine Diagnostics Incorporated | Other Services (except Public Administration) | $199,512 | $201,026 | 13 | <$5M | Research |
| Concentra Solutions INC | Professional, Scientific, and Technical Services | $197,249 | $199,551 | 49 | $5.1M | Research |
| Machine Diagnostics Incorporated | Manufacturing | $193,380 | $194,715 | 13 | <$5M | Research |
| Windsor Hotel Americus, Inc. | Accommodation and Food Services | $191,295 | $192,513 | 48 | $15.0M | Research |
| Odum Sales LLC | Manufacturing | $188,595 | $190,248 | 23 | $6.4M | Research |
| Concentra Solutions INC | Administrative and Support and Waste Management | $186,449 | $188,354 | 49 | $9.3M | Research |
| Southeast Railcar, Inc. | Transportation and Warehousing | $172,944 | $174,242 | 18 | <$5M | Research |