| Mitchell County Hospital Health Systems | Health Care and Social Assistance | $3,032,382 | $2,982,147 | 250 | N/A | Research |
| Carrico Implement Co., Inc. | Wholesale Trade | $1,236,683 | $1,248,843 | 88 | $27.0M | Research |
| Rolling Hills Electric Coop Inc. | Utilities | $1,019,900 | $1,030,836 | 42 | N/A | Research |
| Heineken Electric Co. Inc. | Construction | $946,405 | $953,477 | 70 | $23.0M | Research |
| Heineken Electric Co., Inc. | Construction | $812,000 | $817,008 | 88 | $29.0M | Research |
| Hilltop Ks Opco LLC | Health Care and Social Assistance | $577,645 | $589,198 | 135 | $23.0M | Research |
| Beloit Medical Center PA | Health Care and Social Assistance | $466,963 | $470,051 | 40 | $12.6M | Research |
| Thompson's Ok Tire Inc. | Retail Trade | $339,671 | $342,180 | 25 | $6.8M | Research |
| Abram Ready Mix, INC | Manufacturing | $311,500 | $314,146 | 36 | $35.7M | Research |
| Pestinger Distributing Co., Inc. | Wholesale Trade | $307,966 | $309,686 | 33 | $8.5M | Research |
| S&s Drugs, Inc. | Retail Trade | $230,008 | $233,037 | 21 | <$5M | Research |
| Finn-Kool INC | Manufacturing | $222,905 | $224,280 | 23 | $5.6M | Research |
| Finn-Kool Inc. | Manufacturing | $215,436 | $216,519 | 25 | $6.5M | Research |
| St John the Baptist Catholic Church | Other Services (except Public Administration) | $215,000 | $216,212 | 29 | N/A | Research |
| Beloit Auto & Truck Plaza Inc. | Retail Trade | $209,700 | $211,424 | 20 | $5.0M | Research |
| Dental Designs of Solomon Valley, P.a. | Health Care and Social Assistance | $202,424 | $203,673 | 14 | <$5M | Research |
| Beloit Auto & Truck Plaza Inc. | Retail Trade | $199,900 | $201,323 | 20 | $5.0M | Research |
| Boettcher Supply INC | Wholesale Trade | $187,421 | $188,522 | 18 | $5.5M | Research |
| Dental Designs of Solomon Valley PA | Health Care and Social Assistance | $187,172 | $188,565 | 14 | <$5M | Research |
| Solomon Valley Veterinary Hospital | Professional, Scientific, and Technical Services | $180,333 | $181,099 | 16 | <$5M | Research |
| Chad J. Thompson O.d. Chartered | Health Care and Social Assistance | $153,092 | $154,359 | 11 | <$5M | Research |
| Chad J. Thompson O.d. Chartered | Health Care and Social Assistance | $136,801 | $137,436 | 15 | <$5M | Research |
| Frasier, Johnson & Martin, LLC | Professional, Scientific, and Technical Services | $121,547 | $122,938 | 10 | <$5M | Research |
| Solomon Rapids Seed INC | Agriculture, Forestry, Fishing and Hunting | $114,283 | $114,839 | 7 | <$5M | Research |
| Solomon Rapids Seed INC | Agriculture, Forestry, Fishing and Hunting | $114,283 | $114,977 | 7 | <$5M | Research |