| Crossland Heavy Contractors INC | Construction | $4,312,700 | $4,363,853 | 314 | $97.3M |  Research |
| Class Ltd | Health Care and Social Assistance | $1,000,000 | $1,008,917 | 218 | N/A | Research |
| Farmers Cooperative Association | Other Services (except Public Administration) | $766,266 | $770,864 | 60 | $11.5M | Research |
| Farmers Cooperative Association | Agriculture, Forestry, Fishing and Hunting | $766,266 | $771,800 | 61 | <$5M | Research |
| Jay Hatfield Certified Used Cars, LLC | Retail Trade | $653,900 | $658,296 | 72 | $18.1M | Research |
| Jay Hatfield Chevrolet Buick, INC | Retail Trade | $372,000 | $374,325 | 33 | $8.3M | Research |
| Jay Hatfield Mobility, LLC | Retail Trade | $302,200 | $304,240 | 26 | $7.0M | Research |
| Jay Hatfield Mobility LLC | Retail Trade | $213,985 | $215,061 | 25 | $6.8M | Research |
| Mike Carpino Ford Columbus INC | Retail Trade | $204,900 | $206,847 | 19 | <$5M | Research |
| Robert D. Herron Jr. DDS P.a. | Health Care and Social Assistance | $161,000 | $162,614 | 18 | <$5M | Research |
| Cherokee County Ambulance Assn, Inc. | Health Care and Social Assistance | $152,930 | $153,992 | 21 | N/A | Research |
| Columbus Communication Services LLC | Information | $151,200 | $152,662 | 12 | <$5M | Research |
| Davis Construction, LLC | Construction | $95,006 | $95,594 | 14 | <$5M | Research |
| Micheal Davis | Construction | $87,431 | $87,914 | 11 | <$5M | Research |
| Evans Drug INC | Retail Trade | $82,000 | $82,503 | 16 | <$5M | Research |
| Gregory Veterinary Services, PA | Professional, Scientific, and Technical Services | $79,200 | $79,673 | 9 | <$5M | Research |
| Sdi of Columbus, Ks, LLC | Accommodation and Food Services | $56,000 | $56,372 | 23 | <$5M | Research |
| Pioneer Stock Farms INC | Agriculture, Forestry, Fishing and Hunting | $50,912 | $51,160 | 6 | <$5M | Research |
| Los Lunas Mexican Restaurant INC | Accommodation and Food Services | $50,822 | $51,070 | 14 | <$5M | Research |
| Epler Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $50,670 | $50,952 | 7 | <$5M | Research |
| Carpino Subway One INC | Accommodation and Food Services | $50,267 | $50,636 | 22 | <$5M | Research |
| H & K Camper Sales, Inc. | Retail Trade | $49,300 | $49,846 | 6 | <$5M | Research |
| Natalini's Automotive, Inc. | Retail Trade | $49,000 | $49,263 | 7 | <$5M | Research |
| Epler Farms, Inc. | Agriculture, Forestry, Fishing and Hunting | $44,671 | $44,907 | 3 | <$5M | Research |
| L & S Crain Farms Inc. | Agriculture, Forestry, Fishing and Hunting | $43,866 | $44,166 | 3 | <$5M | Research |