| Fredonia Regional Hospital | Health Care and Social Assistance | $1,068,372 | $1,081,281 | 120 | $23.8M |  Research |
| Fredonia Regional Hospital | Health Care and Social Assistance | $1,068,372 | $1,079,382 | 123 | $24.4M | Research |
| Tindle Construction INC | Construction | $955,300 | $962,597 | 93 | $34.8M | Research |
| Home Town Health Care, LLC | Health Care and Social Assistance | $518,000 | $521,784 | 130 | $22.3M | Research |
| R.k. Steel, INC | Manufacturing | $513,500 | $516,339 | 50 | $12.2M | Research |
| Koehn Construction Services LLC | Construction | $309,200 | $311,639 | 25 | $28.5M | Research |
| Dunn's Material Handling LLC | Transportation and Warehousing | $142,500 | $143,042 | 19 | <$5M | Research |
| Dunn's Material Handling LLC | Mining, Quarrying, and Oil and Gas Extraction | $142,500 | $143,541 | 20 | <$5M | Research |
| Drs. Morris & Hill Medical Clinic, LLC | Health Care and Social Assistance | $133,551 | $134,371 | 14 | <$5M | Research |
| Morningstar Care Homes, LLC | Health Care and Social Assistance | $124,793 | $125,989 | 23 | <$5M | Research |
| Fredonia Pharmacy, Inc. | Retail Trade | $121,600 | $121,521 | 8 | <$5M | Research |
| Jennifer Bacani Mckenney MD LLC | Health Care and Social Assistance | $97,900 | $98,602 | 15 | <$5M | Research |
| Cmac Investments LLC | Accommodation and Food Services | $90,500 | $90,877 | 21 | <$5M | Research |
| Fredonia Livestock Auction,llc | Agriculture, Forestry, Fishing and Hunting | $82,100 | $82,672 | 14 | <$5M | Research |
| Krazy K INC | Transportation and Warehousing | $74,750 | $75,792 | 2 | <$5M | Research |
| Dt Metal Masters, LLC | Manufacturing | $70,000 | $70,751 | 6 | <$5M | Research |
| Cmac Investments, LLC | Real Estate and Rental and Leasing | $64,600 | $65,047 | 28 | <$5M | Research |
| Starbuck Trucking, LLC | Transportation and Warehousing | $59,000 | $59,294 | 7 | <$5M | Research |
| Public Wholesale Water Supply District No. 23 | Utilities | $56,971 | $57,180 | 6 | N/A | Research |
| Dt Metal Masters LLC | Manufacturing | $56,900 | $57,132 | 6 | <$5M | Research |
| Fredonia Hardware, LLC | Retail Trade | $50,800 | $51,213 | 11 | <$5M | Research |
| R. Guy Cleverley, Dds, PA | Health Care and Social Assistance | $49,908 | $49,341 | 4 | <$5M | Research |
| Sdi of Fredonia LLC | Accommodation and Food Services | $42,700 | $43,031 | 30 | $5.3M | Research |
| The Kitchen Table, LLC | Accommodation and Food Services | $42,700 | $43,057 | 7 | <$5M | Research |
| Roger Jantz | Agriculture, Forestry, Fishing and Hunting | $36,300 | $36,548 | 1 | <$5M | Research |