| Labette County Medical Center | Health Care and Social Assistance | $6,370,100 | $1,999,471 | 500 | N/A |  Research |
| Tank Connection LLC | Wholesale Trade | $3,072,900 | $3,116,262 | 265 | $81.2M | Research |
| Beachner Grain, Inc. | Wholesale Trade | $2,658,000 | $2,696,615 | 210 | $54.1M | Research |
| Pete's of Erie, Inc. | Retail Trade | $2,218,000 | $2,235,929 | 313 | $104.7M | Research |
| Grandview Products Company, Inc. | Manufacturing | $1,770,218 | $1,790,588 | 247 | $64.7M | Research |
| Magnum System Inc. | Manufacturing | $1,268,025 | $1,275,281 | 85 | $22.3M | Research |
| Magnum Systems INC | Manufacturing | $1,253,200 | $1,259,953 | 79 | $20.7M | Research |
| Labette Center for Mental Health Services, Inc. | Health Care and Social Assistance | $550,300 | $553,768 | 58 | N/A | Research |
| Woodworth Enterprises, Inc. | Health Care and Social Assistance | $545,487 | $548,624 | 103 | $17.5M | Research |
| Residential Treatment Services of Southeast Kansas LLC | Health Care and Social Assistance | $530,915 | $532,640 | 79 | $12.8M | Research |
| Residential Treatment Serv of SE Ks LLC | Health Care and Social Assistance | $483,834 | $486,549 | 98 | $16.8M | Research |
| Southeast Kansas Independent Living Resource Center, Inc. | Health Care and Social Assistance | $471,500 | $474,923 | 86 | N/A | Research |
| Ray Productsinc. | Manufacturing | $447,043 | $450,433 | 47 | $46.6M | Research |
| Ray Products INC | Manufacturing | $365,100 | $367,199 | 38 | $37.7M | Research |
| Babcock Manufacturing, LLC | Retail Trade | $253,900 | $194,180 | 30 | $6.2M | Research |
| Tom Davis Auto Group, LLC | Retail Trade | $226,982 | $228,502 | 22 | $5.5M | Research |
| Southeast Kansas Orthopedic Clinic | Health Care and Social Assistance | $190,832 | $191,951 | 13 | <$5M | Research |
| Laforge and Budd Construction, INC | Construction | $179,700 | $0 | 9 | $10.3M | Research |
| Ernesto's Mexican Food Inc. | Accommodation and Food Services | $176,151 | $177,766 | 13 | <$5M | Research |
| Alliance Constructors INC | Construction | $168,450 | $169,437 | 12 | <$5M | Research |
| Kitchen Pass INC | Accommodation and Food Services | $164,566 | $166,139 | 43 | $7.6M | Research |
| Ace Hardware INC | Retail Trade | $164,464 | $165,547 | 11 | <$5M | Research |
| Bowen Pharmacy, INC | Retail Trade | $151,900 | $152,736 | 14 | <$5M | Research |
| A & R Custom Forms & Fabrication LLC | Manufacturing | $145,895 | $144,022 | 19 | <$5M | Research |
| H&h Design and Manufacturing, INC | Professional, Scientific, and Technical Services | $145,300 | $146,236 | 13 | <$5M | Research |