| Dianne Wroten Ins. Agency Inc. | Finance and Insurance | $76,300 | $76,718 | 8 | <$5M |  Research |
| Fun and Tumble | Arts, Entertainment, and Recreation | $74,210 | $74,997 | 3 | <$5M | Research |
| Hoard Medical Transportation LLC | Transportation and Warehousing | $74,208 | $74,488 | 4 | <$5M | Research |
| Hibbs Company, LLC | Transportation and Warehousing | $72,977 | $73,476 | 15 | <$5M | Research |
| Franklin Cotton Warehouse Cooperative, Inc. | Transportation and Warehousing | $72,138 | $72,863 | 9 | <$5M | Research |
| Fbp Transortation Services, LLC | Transportation and Warehousing | $71,865 | $41,228 | 10 | <$5M | Research |
| Nelson Tractor Company | Retail Trade | $71,280 | $71,668 | 6 | <$5M | Research |
| American Pipeline Security | Administrative and Support and Waste Management | $71,250 | $71,628 | 39 | $5.7M | Research |
| American Pipeline Security, LLC | Administrative and Support and Waste Management | $71,250 | $71,652 | 39 | $5.7M | Research |
| Browning Gin Company INC | Agriculture, Forestry, Fishing and Hunting | $67,695 | $68,075 | 4 | <$5M | Research |
| Browning Gin Co., INC | Agriculture, Forestry, Fishing and Hunting | $67,695 | $68,415 | 4 | <$5M | Research |
| Collins Plumbing | Construction | $66,200 | $66,715 | 11 | <$5M | Research |
| Crowville Gas & Tire Center, LLC | Retail Trade | $65,258 | $65,624 | 7 | <$5M | Research |
| Joshua Lynch | Construction | $65,115 | $0 | 4 | <$5M | Research |
| Quad D Electric, LLC | Construction | $63,112 | $63,514 | 16 | $5.3M | Research |
| Heather Wallace | Manufacturing | $62,500 | $20,883 | 6 | <$5M | Research |
| Swain Investments LLC | Retail Trade | $62,499 | $62,809 | 3 | <$5M | Research |
| American Fast Lane LLC | Retail Trade | $60,900 | $61,480 | 13 | <$5M | Research |
| Talley Veterinary Services Group Apc | Professional, Scientific, and Technical Services | $58,720 | $59,141 | 8 | <$5M | Research |
| John T. Little a Professional Dental Corp | Health Care and Social Assistance | $58,692 | $59,297 | 8 | <$5M | Research |
| John T Little a Professional Dental Corporation | Health Care and Social Assistance | $58,692 | $59,499 | 8 | <$5M | Research |
| Temple Baptist Church of Winnsboro, Inc. | Other Services (except Public Administration) | $56,365 | $56,713 | 21 | N/A | Research |
| Clark Appraisal Service | Real Estate and Rental and Leasing | $55,567 | $55,837 | 4 | <$5M | Research |
| Jrc Enterprises | Retail Trade | $55,280 | $55,852 | 15 | $5.0M | Research |
| Winnsboro Physical Therapy Inc. | Health Care and Social Assistance | $55,172 | $55,795 | 6 | <$5M | Research |