| East Baking Company, Inc. | Accommodation and Food Services | $450,364 | $453,720 | 16 | <$5M | Research |
| Gateway Office Furniture LLC | Retail Trade | $450,000 | $455,800 | 33 | $6.0M | Research |
| Springdale Education Center, Inc. | Educational Services | $437,200 | $440,853 | 47 | $5.6M | Research |
| Meridian Industrial Group, LLC | Manufacturing | $432,741 | $419,139 | 21 | $5.1M | Research |
| Fln-Mar Rubber & Plastics, Inc. | Wholesale Trade | $420,300 | $423,363 | 29 | $8.9M | Research |
| William F. Sullivan & Co., Inc. | Wholesale Trade | $412,292 | $415,282 | 22 | $6.7M | Research |
| William F Sullivan & Co INC | Wholesale Trade | $412,290 | $415,382 | 22 | $5.7M | Research |
| Hampden County Career Center, Inc. | Health Care and Social Assistance | $399,900 | $258,915 | 46 | N/A | Research |
| New England Ultimate Finishing INC | Manufacturing | $395,500 | $329,233 | 37 | $36.7M | Research |
| Providence Place, Inc. | Health Care and Social Assistance | $380,000 | $382,915 | 36 | N/A | Research |
| Conklin Office Services, Inc. | Retail Trade | $366,040 | $368,917 | 58 | $13.7M | Research |
| Meridian Industrial Group LLC | Manufacturing | $357,507 | $358,976 | 22 | $5.4M | Research |
| G&h Landscaping Inc. | Administrative and Support and Waste Management | $355,000 | $356,903 | 47 | $10.2M | Research |
| Hadley Printing, Co INC | Manufacturing | $336,290 | $338,732 | 36 | $35.7M | Research |
| Bzd Dental Associates, P.c. | Health Care and Social Assistance | $335,900 | $338,486 | 29 | $6.7M | Research |
| The Holyoke Young Men's Christian Association | Other Services (except Public Administration) | $333,505 | $336,414 | 44 | N/A | Research |
| New England Ultimate Finishing INC | Manufacturing | $326,050 | $330,284 | 20 | $19.8M | Research |
| Mid Transport, INC | Transportation and Warehousing | $321,688 | $323,883 | 14 | <$5M | Research |
| Hadley Printing Co INC | Manufacturing | $315,850 | $317,667 | 32 | $31.7M | Research |
| Positive Results, LLC | Professional, Scientific, and Technical Services | $315,600 | $319,102 | 46 | $14.6M | Research |
| New England Etching Co, Inc. | Manufacturing | $313,723 | $316,319 | 18 | <$5M | Research |
| Uni-Pac INC | Manufacturing | $300,745 | $302,426 | 31 | $30.7M | Research |
| Nova Leap Health Ma Ii, Inc. | Health Care and Social Assistance | $292,700 | $294,192 | 62 | $10.6M | Research |
| 110 Grill Hm Holyoke LLC | Accommodation and Food Services | $280,800 | $282,274 | 65 | $11.5M | Research |
| Dr. Minghao Eric Chen, P.c. | Unknown | $274,180 | $231,194 | 21 | N/A | Research |