| Gulf Coast Produce Distributor | Wholesale Trade | $533,379 | $537,748 | 62 | $16.0M |  AI Deep Dive |
| Machado-Patano, Pllc | Professional, Scientific, and Technical Services | $503,200 | $506,440 | 30 | <$5M | AI Deep Dive |
| The Reef of Biloxi LLC | Accommodation and Food Services | $501,635 | $505,996 | 106 | $18.8M | AI Deep Dive |
| Mcelroy's Harbor House Rest. | Accommodation and Food Services | $474,658 | $478,117 | 103 | $18.3M | AI Deep Dive |
| Machado Patano Pllc | Professional, Scientific, and Technical Services | $468,745 | $474,486 | 33 | $10.2M | AI Deep Dive |
| Holden Earth Moving & Construction Company | Construction | $467,248 | $472,049 | 28 | $10.5M | AI Deep Dive |
| Page, Mannino, Peresich & Mcdermott Pllc | Professional, Scientific, and Technical Services | $465,425 | $468,011 | 41 | $10.0M | AI Deep Dive |
| Lucy's Biloxi LLC | Accommodation and Food Services | $462,518 | $468,182 | 267 | $47.4M | AI Deep Dive |
| Hobbs Construction of Ms, LLC | Construction | $441,654 | $344,356 | 29 | $33.0M | AI Deep Dive |
| Mary Mahoney's, Inc. | Accommodation and Food Services | $440,583 | $443,874 | 85 | $15.1M | AI Deep Dive |
| Lli, LLC | Real Estate and Rental and Leasing | $436,137 | $439,709 | 78 | $11.7M | AI Deep Dive |
| Lli, LLC | Construction | $436,137 | $441,964 | 78 | $88.9M | AI Deep Dive |
| St Patrick Catholic High School | Educational Services | $427,157 | $429,922 | 44 | N/A | AI Deep Dive |
| St. Patrick Catholic High School | Educational Services | $427,100 | $431,252 | 44 | N/A | AI Deep Dive |
| Coast Cardiovascular | Health Care and Social Assistance | $426,942 | $430,346 | 35 | $11.0M | AI Deep Dive |
| Barrington Development, LLC | Accommodation and Food Services | $425,554 | $431,228 | 50 | $15.6M | AI Deep Dive |
| Orocon Construction, LLC | Construction | $400,370 | $404,174 | 30 | $34.2M | AI Deep Dive |
| Half Shell Oyster House Biloxi, LLC | Accommodation and Food Services | $395,465 | $398,036 | 73 | $13.0M | AI Deep Dive |
| Slap Ya Mommas INC | Accommodation and Food Services | $390,544 | $395,176 | 30 | $5.3M | AI Deep Dive |
| Mississippi Coast Coliseum and Convention Center | Administrative and Support and Waste Management | $387,840 | $392,558 | 70 | $13.2M | AI Deep Dive |
| Mississippi Coast Coliseum and Convention Center | Administrative and Support and Waste Management | $387,840 | $391,912 | 70 | $13.2M | AI Deep Dive |
| Cedar Lake Christian Assembly | Other Services (except Public Administration) | $376,391 | $378,745 | 57 | N/A | AI Deep Dive |
| Gulf Pride Enterprises INC | Manufacturing | $370,100 | $373,182 | 35 | $12.4M | AI Deep Dive |
| Praetorian Health Services LLC | Health Care and Social Assistance | $365,433 | $368,136 | 66 | $11.3M | AI Deep Dive |
| Praetorian Health Services, LLC | Health Care and Social Assistance | $365,433 | $368,416 | 79 | $13.5M | AI Deep Dive |