| Quality Cabinet Company Incorporated | Manufacturing | $120,625 | $121,362 | 20 | $5.2M |  Research |
| Sonic Drive-In, Hernando, Ms, LLC | Accommodation and Food Services | $120,143 | $122,686 | 61 | $10.8M | Research |
| Holden Integrated Services LLC | Construction | $115,988 | $117,163 | 11 | <$5M | Research |
| Bobbitt Mechanical INC | Construction | $115,700 | $0 | 10 | <$5M | Research |
| Grassland INC | Utilities | $113,873 | $114,269 | 13 | N/A | Research |
| Ac Management Group, LLC | Accommodation and Food Services | $112,600 | $113,726 | 35 | $6.2M | Research |
| Hernando Golf & Racquet Club LLC | Arts, Entertainment, and Recreation | $109,500 | $110,607 | 31 | <$5M | Research |
| Tri-County Farm Services, INC | Wholesale Trade | $108,832 | $109,440 | 23 | $5.9M | Research |
| Desoto County Economic Development Council | Public Administration | $108,760 | $109,552 | 4 | N/A | Research |
| Chatham Gilder Howell Pittman Pllc | Professional, Scientific, and Technical Services | $107,694 | $108,208 | 8 | <$5M | Research |
| Hernando Family Medical Clinic, LLC | Health Care and Social Assistance | $107,500 | $108,210 | 10 | <$5M | Research |
| Community Foundation of Northwest Mississippi | Other Services (except Public Administration) | $107,040 | $107,407 | 8 | N/A | Research |
| Riac Entertainment Corporation | Accommodation and Food Services | $106,300 | $107,059 | 33 | $5.9M | Research |
| Tidwell Enterprises LLC | Retail Trade | $105,900 | $106,809 | 14 | <$5M | Research |
| National Tank INC | Manufacturing | $104,989 | $105,282 | 11 | <$5M | Research |
| Hernando Hotel Group, LLC | Accommodation and Food Services | $102,395 | $103,247 | 24 | $7.5M | Research |
| Southern Air Conditioning & Heating, Inc. | Construction | $101,810 | $102,479 | 12 | <$5M | Research |
| Southern Air Conditioning & Heating Inc. | Construction | $101,785 | $102,248 | 12 | <$5M | Research |
| Grassland, Inc. | Construction | $100,800 | $101,858 | 16 | <$5M | Research |
| Timothy Williams | Construction | $100,540 | $101,411 | 11 | <$5M | Research |
| Buon Cibo LLC | Accommodation and Food Services | $98,729 | $99,172 | 25 | <$5M | Research |
| Orion Planning & Design LLC | Professional, Scientific, and Technical Services | $98,719 | $99,766 | 6 | <$5M | Research |
| Ag Integral LLC | Professional, Scientific, and Technical Services | $98,675 | $99,194 | 7 | <$5M | Research |
| Fowler Engineering LLC | Professional, Scientific, and Technical Services | $95,400 | $96,093 | 6 | <$5M | Research |
| Ag Integral LLC | Real Estate and Rental and Leasing | $94,500 | $95,284 | 7 | <$5M | Research |