| Cairo Marine Service, INC | Transportation and Warehousing | $177,700 | $178,786 | 12 | <$5M |  Research |
| T & W Masonry LLC | Construction | $176,667 | $177,648 | 11 | <$5M | Research |
| Tom Beussink Excavating, Inc. | Construction | $176,100 | $177,274 | 23 | $7.1M | Research |
| Cairo Marine Service Inc. | Public Administration | $173,500 | $174,536 | 12 | N/A | Research |
| Translectric, Inc. | Wholesale Trade | $172,800 | $173,785 | 14 | <$5M | Research |
| Trendline Consulting LLC | Professional, Scientific, and Technical Services | $161,600 | $163,993 | 35 | <$5M | Research |
| Wings of Jackson LLC | Accommodation and Food Services | $158,100 | $159,317 | 46 | $8.2M | Research |
| Mccombs Funeral Home, Inc. | Other Services (except Public Administration) | $157,872 | $158,924 | 13 | <$5M | Research |
| Flickerwood Farms INC | Manufacturing | $156,159 | $157,581 | 16 | $15.9M | Research |
| United Land Title, LLC | Real Estate and Rental and Leasing | $156,000 | $157,291 | 22 | <$5M | Research |
| Shawneetown Feed & Seed Co. | Wholesale Trade | $146,587 | $148,118 | 16 | <$5M | Research |
| Shawneetown Feed & Seed Co | Wholesale Trade | $144,100 | $145,269 | 15 | <$5M | Research |
| Coast to Coast Signs LLC | Manufacturing | $137,500 | $138,478 | 15 | <$5M | Research |
| Hickory House Restaurant Inc. | Accommodation and Food Services | $132,874 | $133,616 | 13 | <$5M | Research |
| Hartle Management Agency, Inc. | Real Estate and Rental and Leasing | $130,200 | $131,110 | 26 | <$5M | Research |
| Agri Systems Services of Cape & Jackson | Retail Trade | $129,292 | $120,674 | 11 | <$5M | Research |
| Copi-Rite, Inc. | Professional, Scientific, and Technical Services | $128,400 | $129,359 | 16 | <$5M | Research |
| G&r Imports, LLC | Retail Trade | $126,815 | $127,900 | 12 | <$5M | Research |
| Tractors Classic American Grill, LLC | Accommodation and Food Services | $126,500 | $127,811 | 20 | <$5M | Research |
| Agri System Service of Cape & Jackson | Retail Trade | $125,760 | $126,170 | 12 | <$5M | Research |
| Cape Cars Auto Group | Wholesale Trade | $124,325 | $124,856 | 13 | <$5M | Research |
| Msi Electic, INC | Construction | $121,800 | $122,608 | 7 | <$5M | Research |
| Deer Ridge Animal Hospital LLC | Professional, Scientific, and Technical Services | $121,549 | $122,369 | 20 | <$5M | Research |
| Mclb Management Company LLC | Administrative and Support and Waste Management | $121,147 | $122,332 | 24 | <$5M | Research |
| Farmington Regional Stockyards, LLC | Wholesale Trade | $114,400 | $115,146 | 32 | $8.2M | Research |