| Subconn, INC | Manufacturing | $849,183 | $853,924 | 118 | $30.9M | Research |
| Community Memorial Hospital INC | Health Care and Social Assistance | $528,535 | $531,603 | 97 | N/A | Research |
| Rowse Hydraulic Rakes Co, Inc. | Manufacturing | $333,757 | $335,991 | 39 | $10.2M | Research |
| Burwell Livestock Market II Ltd | Agriculture, Forestry, Fishing and Hunting | $189,462 | $190,294 | 49 | <$5M | Research |
| Burwell Livestock Market II Ltd | Agriculture, Forestry, Fishing and Hunting | $189,400 | $190,463 | 49 | <$5M | Research |
| Burwell Feeders LLC | Agriculture, Forestry, Fishing and Hunting | $178,800 | $179,922 | 12 | <$5M | Research |
| Maverick Truck Stop & Cafe INC | Retail Trade | $169,004 | $169,408 | 28 | $9.4M | Research |
| Burwell Feeders LLC | Agriculture, Forestry, Fishing and Hunting | $141,998 | $142,818 | 13 | <$5M | Research |
| Jeffres Sand and Gravel INC | Mining, Quarrying, and Oil and Gas Extraction | $106,485 | $107,083 | 14 | <$5M | Research |
| Jeffres Trucking LLC | Transportation and Warehousing | $97,090 | $97,635 | 10 | <$5M | Research |
| Thoene Farm Service INC | Other Services (except Public Administration) | $96,000 | $96,905 | 10 | <$5M | Research |
| Burwell Economy Market Inc. | Retail Trade | $75,823 | $76,299 | 23 | $5.7M | Research |
| Spelts Lumber Co of Burwell | Retail Trade | $70,242 | $70,789 | 7 | <$5M | Research |
| Burwell Dental Clinic, PC | Health Care and Social Assistance | $67,500 | $68,064 | 10 | <$5M | Research |
| Burwell Dental Clinic PC | Health Care and Social Assistance | $67,500 | $68,117 | 9 | <$5M | Research |
| Burwell Family Practice P.c. | Health Care and Social Assistance | $60,893 | $61,267 | 7 | <$5M | Research |
| Burwell Family Practice PC | Health Care and Social Assistance | $60,893 | $61,384 | 7 | <$5M | Research |
| Burwell Veterinary Hospital | Professional, Scientific, and Technical Services | $57,400 | $57,682 | 8 | <$5M | Research |
| M & R Cattle Company Inc. | Agriculture, Forestry, Fishing and Hunting | $54,100 | $54,760 | 8 | <$5M | Research |
| Jeffres & Sons INC | Agriculture, Forestry, Fishing and Hunting | $53,400 | $53,654 | 13 | <$5M | Research |
| Olcott & Sons, INC | Other Services (except Public Administration) | $48,992 | $49,091 | 7 | <$5M | Research |
| Rowdy Express, INC | Transportation and Warehousing | $46,297 | $46,602 | 5 | <$5M | Research |
| Loup Valley Redi Mix, LLC | Manufacturing | $43,295 | $43,538 | 7 | $6.9M | Research |
| Burwell Pharmacy LLC | Retail Trade | $42,590 | $42,917 | 7 | <$5M | Research |
| Switzer Ranch Backgrounding LLC | Agriculture, Forestry, Fishing and Hunting | $40,700 | $40,880 | 2 | <$5M | Research |