| Landmark Implement, INC | Wholesale Trade | $6,074,000 | $6,143,893 | 375 | $114.9M | Research |
| Phelps Memorial Health Center | Health Care and Social Assistance | $2,935,000 | $2,969,014 | 258 | N/A | Research |
| Nebraska Provider Alliance, LLC | Professional, Scientific, and Technical Services | $1,289,955 | $1,301,936 | 147 | $15.2M | Research |
| Christian Homes Inc. | Health Care and Social Assistance | $1,171,742 | $1,181,276 | 124 | N/A | Research |
| Holdrege Memorial Homes, Inc. | Health Care and Social Assistance | $1,034,500 | $1,040,792 | 145 | $24.7M | Research |
| Christian Homes, Inc. | Health Care and Social Assistance | $873,712 | $818,967 | 150 | N/A | Research |
| Agwest Commodities LLC | Finance and Insurance | $813,285 | $816,093 | 47 | $24.1M | Research |
| Agwest Commodities LLC | Finance and Insurance | $708,010 | $712,025 | 47 | $24.1M | Research |
| Central Valley Irrigation, Inc. | Utilities | $596,600 | $600,899 | 38 | N/A | Research |
| Phelps County Feeders, LLC | Agriculture, Forestry, Fishing and Hunting | $582,900 | $586,217 | 50 | $8.2M | Research |
| Holdrege Irrigation INC | Utilities | $548,297 | $551,053 | 55 | N/A | Research |
| Holdrege Irrigation, Inc. | Wholesale Trade | $540,000 | $543,135 | 48 | $14.7M | Research |
| Westerlin-Harrington Flying Service Inc. | Manufacturing | $437,400 | $439,150 | 26 | $25.8M | Research |
| Westerlin-Harrington Flying Servce, Inc. | Wholesale Trade | $388,700 | $390,946 | 32 | $8.2M | Research |
| Lloyd Waller Feedyard LLC | Agriculture, Forestry, Fishing and Hunting | $340,406 | $342,598 | 21 | <$5M | Research |
| Alarado Enterprises, LLC | Accommodation and Food Services | $315,013 | $316,938 | 69 | $12.3M | Research |
| Ymca of the Prairie | Other Services (except Public Administration) | $256,800 | $259,839 | 148 | N/A | Research |
| Ymca of the Prairie | Arts, Entertainment, and Recreation | $250,702 | $251,635 | 134 | N/A | Research |
| Lee Janssen Motor Company | Retail Trade | $248,900 | $251,327 | 25 | $6.3M | Research |
| Holdrege Medical Clinic, P. C. | Health Care and Social Assistance | $234,200 | $236,799 | 8 | <$5M | Research |
| Alarado Enterprises, LLC | Accommodation and Food Services | $216,750 | $218,008 | 61 | $10.8M | Research |
| Janssen and Sons INC | Retail Trade | $212,400 | $214,489 | 17 | <$5M | Research |
| Rite Way Milk Inc. | Transportation and Warehousing | $200,000 | $201,244 | 14 | <$5M | Research |
| South Central Diesel INC | Other Services (except Public Administration) | $188,600 | $189,713 | 14 | <$5M | Research |
| Holdrege Well Service, LLC | Construction | $175,800 | $176,835 | 19 | $5.9M | Research |