| St. Patrick School System | Educational Services | $365,600 | $370,017 | 44 | N/A | AI Deep Dive |
| Midlands Family Medicine | Health Care and Social Assistance | $352,973 | $355,708 | 38 | $11.9M | AI Deep Dive |
| Beveridge Well Drilling, Inc. | Construction | $329,100 | $330,930 | 22 | $7.5M | AI Deep Dive |
| Janssen Brothers LLC | Retail Trade | $328,100 | $331,326 | 26 | $6.6M | AI Deep Dive |
| Priority Medical Transport, LLC | Health Care and Social Assistance | $307,900 | $311,924 | 25 | $5.8M | AI Deep Dive |
| Neff Investments LLC | Accommodation and Food Services | $294,664 | $296,424 | 44 | $7.8M | AI Deep Dive |
| North Platte Pharmacy INC | Retail Trade | $294,041 | $295,797 | 22 | <$5M | AI Deep Dive |
| Mcchesney Martin Sagehorn, PC | Professional, Scientific, and Technical Services | $282,344 | $285,183 | 23 | $7.3M | AI Deep Dive |
| Jerry Remus Chevrolet Cadillac, LLC | Retail Trade | $278,500 | $280,423 | 31 | $7.8M | AI Deep Dive |
| North Platte Lodging Ltd | Accommodation and Food Services | $273,300 | $276,078 | 37 | $11.6M | AI Deep Dive |
| Skiles Loop Bremer & White Cpas, PC | Professional, Scientific, and Technical Services | $257,600 | $259,033 | 23 | $7.3M | AI Deep Dive |
| Guardian Light Family Services, LLC | Health Care and Social Assistance | $256,100 | $258,093 | 38 | $6.2M | AI Deep Dive |
| A-J Sheet Metal Inc. | Construction | $251,000 | $342,051 | 32 | $10.1M | AI Deep Dive |
| Steele Roofing & Construction, Inc. | Construction | $250,800 | $252,416 | 24 | $27.3M | AI Deep Dive |
| Coors Distributing Company of North Platte, Inc. | Wholesale Trade | $236,300 | $239,200 | 21 | $5.4M | AI Deep Dive |
| Neff Investments | Accommodation and Food Services | $231,175 | $233,146 | 48 | $8.5M | AI Deep Dive |
| Mentzer Oil Company | Wholesale Trade | $227,537 | $230,103 | 20 | $5.1M | AI Deep Dive |
| Three Cedars INC | Health Care and Social Assistance | $216,260 | $218,741 | 90 | $15.4M | AI Deep Dive |
| K & S Electric INC | Construction | $213,866 | $216,147 | 25 | $8.2M | AI Deep Dive |
| Title Services of the Plains LLC | Professional, Scientific, and Technical Services | $210,100 | $211,553 | 26 | $7.1M | AI Deep Dive |
| Levander's of North Platte, L.l.c. | Other Services (except Public Administration) | $209,800 | $211,111 | 16 | <$5M | AI Deep Dive |
| Wilkinson Lodging, L.l.c. | Accommodation and Food Services | $209,614 | $210,717 | 18 | $5.6M | AI Deep Dive |
| Family Skill Building Services LLC | Health Care and Social Assistance | $206,052 | $208,216 | 34 | $5.5M | AI Deep Dive |
| Westfield Pharmacy INC | Retail Trade | $203,702 | $204,935 | 26 | <$5M | AI Deep Dive |
| 4th Generation Development INC | Accommodation and Food Services | $198,950 | $200,072 | 33 | $10.3M | AI Deep Dive |