| Valley County Hospital | Health Care and Social Assistance | $2,312,000 | $2,339,102 | 209 | N/A | Research |
| Valley View Senior Village | Health Care and Social Assistance | $324,000 | $325,968 | 50 | $8.5M | Research |
| Severson, Lammers, & Abel, Cpa's PC | Professional, Scientific, and Technical Services | $156,641 | $157,537 | 14 | <$5M | Research |
| Nebraska Distillers Products LLC | Manufacturing | $148,625 | $149,719 | 14 | <$5M | Research |
| Valley Transportation, LLC | Retail Trade | $147,772 | $148,650 | 11 | <$5M | Research |
| Good Life Health Services INC | Retail Trade | $146,600 | $147,455 | 16 | <$5M | Research |
| The Parts Bin, Inc. | Retail Trade | $145,032 | $146,305 | 14 | <$5M | Research |
| Triple T Farms LLC | Agriculture, Forestry, Fishing and Hunting | $123,800 | $124,667 | 12 | <$5M | Research |
| Grand Living Alternatives | Health Care and Social Assistance | $121,630 | $122,333 | 22 | <$5M | Research |
| Ord Veterinary Clinic PC | Professional, Scientific, and Technical Services | $111,355 | $112,334 | 10 | <$5M | Research |
| Triple T Farms LLC | Agriculture, Forestry, Fishing and Hunting | $110,422 | $111,063 | 15 | <$5M | Research |
| Agland Electric & Irrigation INC | Retail Trade | $109,000 | $109,615 | 9 | <$5M | Research |
| Stowell, Geweke & Piskorski P.c. L.l.o. | Professional, Scientific, and Technical Services | $102,175 | $102,856 | 14 | <$5M | Research |
| Ulrich Gravel, Inc. | Mining, Quarrying, and Oil and Gas Extraction | $97,774 | $98,328 | 7 | <$5M | Research |
| Blaha & Blaha, Inc. | Retail Trade | $96,562 | $97,216 | 16 | <$5M | Research |
| Hackel Construction Inc. | Construction | $95,207 | $95,533 | 11 | $12.5M | Research |
| Bonanza Cattle Company LLC | Agriculture, Forestry, Fishing and Hunting | $93,500 | $94,097 | 8 | <$5M | Research |
| G3 Contracting, Inc. | Construction | $87,300 | $87,799 | 15 | <$5M | Research |
| Bonanza Cattle Company LLC | Agriculture, Forestry, Fishing and Hunting | $84,959 | $85,450 | 8 | <$5M | Research |
| Loup Valley Dental PC | Health Care and Social Assistance | $78,182 | $78,575 | 10 | <$5M | Research |
| Loup Valley Dental PC | Other Services (except Public Administration) | $78,100 | $78,478 | 10 | <$5M | Research |
| Jay Knapp | Agriculture, Forestry, Fishing and Hunting | $76,900 | $77,285 | 8 | <$5M | Research |
| G3 Contracting, Inc. | Construction | $76,580 | $76,891 | 15 | $17.1M | Research |
| Hackel Construction, Inc. | Construction | $74,261 | $74,748 | 8 | $9.1M | Research |
| Brandon A. Blair O.d. P.c | Health Care and Social Assistance | $73,500 | $73,929 | 8 | <$5M | Research |