| Aspire of Western New York Inc. | Health Care and Social Assistance | $10,000,000 | $10,095,616 | 500 | $81.0M |  Research |
| Horizon Health Services Inc. | Health Care and Social Assistance | $5,334,310 | $5,397,737 | 405 | N/A | Research |
| The Summit Center, Inc. | Educational Services | $4,674,100 | $4,736,976 | 462 | N/A | Research |
| Beechwood Health Care Center, Inc. | Health Care and Social Assistance | $4,009,600 | $4,061,121 | 500 | N/A | Research |
| Menorah Campus, Inc. | Health Care and Social Assistance | $3,143,517 | $3,676,557 | 438 | N/A | Research |
| Kelton Enterprises, LLC | Accommodation and Food Services | $2,587,600 | $2,617,375 | 500 | $88.8M | Research |
| Horizon Village INC | Health Care and Social Assistance | $2,106,487 | $2,132,284 | 172 | N/A | Research |
| West Herr Ford of Amherst, LLC | Retail Trade | $1,826,430 | $1,847,196 | 157 | $39.6M | Research |
| Atto Technology, Inc. | Manufacturing | $1,815,300 | $1,835,094 | 118 | $30.9M | Research |
| Atto Technology Inc. | Manufacturing | $1,774,840 | $1,786,267 | 118 | $30.9M | Research |
| Hogan & Willig, Pllc | Professional, Scientific, and Technical Services | $1,149,800 | $1,166,153 | 75 | $18.2M | Research |
| Jewish Community Center of Greater Buffalo, Inc. | Arts, Entertainment, and Recreation | $1,127,600 | $1,135,848 | 336 | N/A | Research |
| Jewish Community Center of Greater Buffalo Inc. | Arts, Entertainment, and Recreation | $1,115,987 | $1,120,757 | 240 | N/A | Research |
| Health Management Group Ltd. | Administrative and Support and Waste Management | $1,048,849 | $1,060,113 | 86 | N/A | Research |
| The Chapel at Crosspoint | Other Services (except Public Administration) | $900,000 | $907,274 | 109 | N/A | Research |
| Virtual Polymer Compounds, LLC | Manufacturing | $533,272 | $540,427 | 38 | $37.7M | Research |
| Trust U/m Martin Fagin C/o Arnald Maxick | Wholesale Trade | $500,900 | $505,580 | 34 | $10.4M | Research |
| Virtual Polymer Compounds, LLC | Wholesale Trade | $495,700 | $440,603 | 39 | $10.0M | Research |
| Largo Real Estate Advisors INC | Finance and Insurance | $449,567 | $452,801 | 29 | $14.9M | Research |
| Everest Receivable Services INC | Professional, Scientific, and Technical Services | $444,627 | $450,121 | 53 | $7.4M | Research |
| Multisource International LLC | Transportation and Warehousing | $386,574 | $391,255 | 26 | <$5M | Research |
| Ashbury Pointe, Inc. | Health Care and Social Assistance | $363,500 | $367,533 | 111 | N/A | Research |
| Largo Real Estate Advisors INC | Finance and Insurance | $357,400 | $355,980 | 25 | $12.8M | Research |
| The Schwartz Group, Inc. | Professional, Scientific, and Technical Services | $324,712 | $326,856 | 36 | <$5M | Research |
| Lebro's Restaurant | Accommodation and Food Services | $294,973 | $298,699 | 39 | $6.9M | Research |