| Notre Dame Elementary School | Educational Services | $207,000 | $209,576 | 36 | N/A |  AI Deep Dive |
| Unity 1 Home Healthcare, LLC | Health Care and Social Assistance | $204,827 | $206,521 | 70 | $12.0M | AI Deep Dive |
| Country Living Home Health Care, Inc. | Health Care and Social Assistance | $204,250 | $203,939 | 115 | $19.7M | AI Deep Dive |
| Portsmouth Vision Center Ltd | Health Care and Social Assistance | $204,162 | $206,797 | 20 | <$5M | AI Deep Dive |
| Tim Short Portsmouth LLC | Retail Trade | $200,500 | $82,421 | 36 | $9.1M | AI Deep Dive |
| Gampp, INC | Retail Trade | $199,382 | $200,696 | 30 | $10.0M | AI Deep Dive |
| Tnhrs INC | Accommodation and Food Services | $196,400 | $197,745 | 58 | $10.3M | AI Deep Dive |
| Morgantown Accommodations Llc. | Accommodation and Food Services | $192,980 | $194,454 | 13 | <$5M | AI Deep Dive |
| Portsmouth Vision Center, Ltd | Health Care and Social Assistance | $192,930 | $194,537 | 17 | <$5M | AI Deep Dive |
| Surviving Our Losses (and Continuing Everyday), INC | Health Care and Social Assistance | $190,900 | $192,714 | 26 | <$5M | AI Deep Dive |
| Tom Barbour Auto Parts, Inc. | Retail Trade | $186,900 | $188,318 | 26 | $7.0M | AI Deep Dive |
| Goodwill Industries of Southern Ohio INC | Retail Trade | $185,450 | $186,568 | 38 | N/A | AI Deep Dive |
| Goodwill Industries of Southern Ohio | Retail Trade | $185,255 | $185,965 | 75 | N/A | AI Deep Dive |
| Schmidt Group Ky INC | Accommodation and Food Services | $177,952 | $180,575 | 76 | $13.5M | AI Deep Dive |
| Reynolds & Company | Professional, Scientific, and Technical Services | $177,737 | $178,698 | 16 | $5.1M | AI Deep Dive |
| Shultz Transport INC | Transportation and Warehousing | $169,445 | $171,172 | 27 | $7.2M | AI Deep Dive |
| Southern Ohio Surgical Associates | Health Care and Social Assistance | $167,000 | $168,089 | 17 | $5.3M | AI Deep Dive |
| Southern Ohio Surgical Associates INC | Health Care and Social Assistance | $167,000 | $168,029 | 17 | $5.3M | AI Deep Dive |
| Livingston and Co INC | Wholesale Trade | $164,900 | $165,647 | 14 | <$5M | AI Deep Dive |
| Livingston & Company Inc. | Wholesale Trade | $164,900 | $165,954 | 11 | <$5M | AI Deep Dive |
| Sole Choice, Inc. | Manufacturing | $162,600 | $164,131 | 33 | $11.6M | AI Deep Dive |
| Sole Choice, Inc. | Manufacturing | $161,070 | $162,573 | 33 | $11.6M | AI Deep Dive |
| Portsmouth Management Firm LLC | Professional, Scientific, and Technical Services | $157,000 | $158,827 | 16 | <$5M | AI Deep Dive |
| Millhuff-Stang CPA Inc. | Professional, Scientific, and Technical Services | $153,147 | $154,065 | 15 | <$5M | AI Deep Dive |
| Burnside Law LLC | Professional, Scientific, and Technical Services | $152,600 | $154,306 | 14 | <$5M | AI Deep Dive |